Maternal Alopecia Aerata and the Risk of Various Offspring Comorbidities
1. Offspring of mothers with alopecia areata had a significantly higher risk of autoimmune, inflammatory, atopic, thyroid, ad psychiatric disorders....
Dermatology
Spironolactone may be effective in the treatment of acne vulgaris
1. Spironolactone showed more effective improvement in acne at 12 and 24 weeks after treatment initiation as compared with the...
Comparing plasmapheresis and immunoglobulin-first therapy for patients with Stevens-Johnson syndrome and toxic epidermal necrolysis who previously received ineffective systemic corticosteroid therapy
1. No significant difference in mortality rates between inpatients with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) who received...
Ritlecitinib superior to placebo in the treatment of alopecia areata among teens and adults
1. Patients in the ritlecitinib group showed significant improvements in alopecia symptoms, with Severity of Alopecia Tool (SALT) scores ≤...
SMiLE Randomized Trial Supports Incorporating Mindfulness and Self-Compassion Training into the Treatment Plan for Adult Patients with Atopic Dermatitis
1. Online mindfulness and self-compassion training, in addition to usual dermatologic care, improved the quality of life, disease symptoms, and...
Delay of surgical treatment for melanoma up to 90 days not associated with poorer outcomes
1. In this retrospective cohort study, cutaneous melanomas with a classification of T1b-T4 but without clinical evidence of metastatic disease (N0M0)...
Phase 2 Randomized Trial Supports Roflumilast as a Potential Treatment for Seborrheic Dermatitis
1. Erythema, scaling, and itching caused by seborrheic dermatitis (SD) significantly decreased with roflumilast treatment. 2. Roflumilast treated for SD...
Phase 1 Randomized Trial Supports Lovastatin as a Potential Primary Treatment for Disseminated Superficial Actinic Porokeratosis
1. Disseminated superficial actinic porokeratosis (DSAP) was improved in both treatment groups (i.e., lovastatin-cholesterol and lovastatin alone) with no serious...
Dersimelagon reduces symptomatic disease in erythropoietic protoporphyrias
1. In this randomized controlled trial, oral dersimelagon resulted in significantly increased time to first symptoms among patients with erythropoietic...
ECZTRA 6 Phase 3 Randomized Trial Supports Tralokinumab for Adolescent Moderate-to-Severe Atopic Dermatitis
1. Interleukin-13 targeted treatment with tralokinumab was effective and well-tolerated for adolescent moderate-to-severe atopic dermatitis. 2. No new safety signals...
