Mirikizumab is safe and effective in patients with moderate-to-severe Crohn’s disease
1. The composite of patient-reported clinical response and endoscopic response was significantly greater in mirikizumab versus placebo. 2. Clinical remission...
Gastroenterology
Reports of high-impact gastroenterology studies by medical professionals
Fecal Microbiota, live-jslm may be an effective means of preventing Clostridiodes difficile infections in patients with inflammatory bowel disease
1. The use of fecal microbiota, live-jslm (RBL; REBYOTA®) in the prevention of recurrent Clostridioides difficile infection (rCDI) in patients...
Esophageal candida infection associated with increased esophageal cancer risk in patients with achalasia
1. Among 234 patients with achalasia, esophageal candidiasis was identified in 12%. 2. Among patients with achalasia, prior esophageal candidiasis,...
5-Aminosalicylic Acid may not be an effective combination with ustekinumab for inflammatory bowel disease
1. Overall, the use of 5-aminosalicylic acid (5-ASA) in combination with ustekinumab (UST) did not provide a significant benefit in...
Probiotic use may decrease risk factors for metabolic syndrome
1. Patients randomized to receive 12 weeks of Lacticaseibacillus paracasei MSMC39-1 and Bifidobacterium animalis TA-1 probiotics were observed to have...
Adalimumab may be associated with improved outcomes in the management of pediatric Crohn’s disease
1. Maintenance therapy with adalimumab (ADA) was associated with more frequent objective improvement based on Magnetic Resonance Enterography (MRE) findings...
Coffee consumption associated with better cognitive performance in patients with atrial fibrillation
Coffee consumption correlates with better cognitive performance in patients with a high incidence for stroke 1. In this cohort of...
Fluorouracil, leucovorin and irinotecan plus panitumumab for the treatment of metastatic colorectal cancer
1. An intermittent strategy with fluorouracil, leucovorin and irinotecan (FOLFIRI) plus panitumumab (PAN) following induction was feasible, showed reduced toxicity...
Grading carcinoembryonic antigen levels can enhance prognostic stratification in colorectal cancer
1. Higher CEA levels in patients with colorectal cancer are indicative of aggressive tumour phenotypes and survival Evidence Rating Level:...
Glucagon-like peptide 1 receptor agonists may decrease rates of inflammatory bowel disease flares
1. The use of glucagon-like peptide 1 (GLP-1) agonists in patients with inflammatory bowel disease (IBD) was associated with few...
