High dose aflibercept reduced treatment burden in patients with diabetic macular edema
1. Aflibercept 8 mg was non-inferior to 2 mg for best-corrected visual acuity at 48 weeks. 2. Ocular adverse events...
Ophthalmology
Reports of high-impact ophthalmology studies by medical professionals
Avacincaptad pegol reduces the rate of age-related macular degeneration in geographic atrophy
1. Avacincaptad pegol significantly slowed geographic atrophy over 12 months. 2. Exudative macular neovascularization was comparable among treatment groups. Evidence...
Immediate bilateral cataract surgery is more cost-effective with similar outcomes compared to delayed sequential surgery
1. Target refractive outcome was achieved in 97% of ISBCS and 98% of DSBCS patients. 2. Societal costs for ISBCS...
Retinopathy of prematurity may account for a large proportion of childhood blindness in the United States
1. In a cross-sectional study using a large clinical registry, retinopathy of prematurity was the most common cause of blindness...
Retinal optical coherence tomography (OCT) measurements may be associated with genetic Alzheimer’s disease risk
1. In a retrospective study examining 50,000 optical coherence tomography (OCT) images from a large database, thicknesses of several different...
Novel anti-VEGF agent provides additional benefit when combined with ranibizumab for neovascular age-related macular degeneration
1. In a phase 2 randomized trial, intravitreal injection with both ranibizumab and OPT-302, a VEGF-C and -D inhibitor, led...
Glucagon-like peptide-1 receptor agonist may reduce incidence of diabetic retinopathy
1. Patients with Type 2 Diabetes taking glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have a lower incidence of diabetic retinopathy...
Age-related macular degeneration may be associated with depression risk
1. In a large population-based cohort, age-related macular degeneration (AMD) diagnosis was associated with increased risk for depression onset. 2....
Risk of hydroxychloroquine retinopathy increases with longer use and higher dosage
1. In this retrospective cohort study, the incidence of hydroxychloroquine retinopathy was 2.5% at 10 years, increasing to 8.6% at...
Community-based adult vision screening program increases access to eye care
1. In a cluster-randomized trial of a community-based program adults living in public housing in New York City, vision screening...
