Voclosporin shows clinical promise for treatment of active lupus nephritis
1. A significantly greater proportion of patients in the voclosporin group achieved complete renal responses after 52 weeks compared to...
Rheumatology
Reduced-dose glucocorticoid adjunct non-inferior to high-dose glucocorticoid plus rituximab regimen for induction of disease remission in autoimmune vasculitis
1. Reduced-dose glucocorticoid plus rituximab regimen was non-inferior compared to high-dose glucocorticoid plus rituximab regimen for induction of disease remission...
Cardiovascular safety of hydroxychloroquine in veterans with rheumatoid arthritis
1. Among a large, matched cohort of veterans with rheumatoid arthritis, initiation of hydroxychloroquine was not associated with a higher...
Upadacitinib non-inferior to adalimumab for psoriatic arthritis treatment
1. Janus kinase (JAK) inhibitor upadacitinib showed non-inferior efficacy in improving psoriatic arthritis compared to standard-of-care adalimumab. 2. High-dose upadacitinib...
Bimekizumab superior to secukinumab for plaque psoriasis treatment
1. Bimekizumab treatment was shown to be noninferior and superior for greater skin clearance of plaque psoriasis compared to secukinumab...