Increased risk of aggressive prostate cancer following vasectomy
1. Vasectomy was associated with a small increased risk of aggressive prostate cancer on extended long-term follow-up.Evidence Rating Level: 2 (Good)Study Rundown: The association...
Novel aromatase inhibitor, ODM-201, may be safe and effective for prostate cancer
1. In a phase I trial, ODM-201 was well tolerated up to 1800mg per day in prostate cancer patients, without reaching the maximum tolerated...
Obesity linked with prostate cancer progression
1. In men with low-risk prostate cancer undergoing active surveillance, obesity (BMI>30) was significantly associated with pathologic and therapeutic progression after the first confirmatory...
Use of 5α-reductase inhibitors may not increase risk of high-grade prostate cancer
Image: PD1. The use of 5α-reductase inhibitors (5ARIs) was not associated with increased risk of developing high-grade or lethal prostate cancer.2. 5ARI use...
Seminal vesicle invasion predicts decreased survival in bladder cancer
1. Concomitant seminal vesicle invasion (cSVI) in patients with urothelial carcinoma of the bladder (UCB) and prostatic stromal infiltration was associated with decreased cancer-specific...
Lower rates of repeat intervention following ureteroscopy for kidney stones
Image: PD 1. 18.7% of patients undergoing ureteroscopy required a second procedure to fragment or remove a kidney stone, compared to 23.6% for patients who...
Tadalafil ineffective for erectile dysfunction following prostate radiotherapy
Image: PD 1. Radiotherapy for prostate cancer treatment often leads to erectile dysfunction. 2. Daily tadalafil during treatment does not have protective effects against the development...
No difference in outcomes following pelvic organ prolapse treatments
Image: PD1. The use of sacrospinous ligament fixation (SSLF) or uterosacral ligament suspension (ULS) for repair of pelvic organ prolapse did not affect outcomes...
2 Minute Medicine Rewind March 02 – 10, 2014
Image:PDIn this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week.Gene Editing of CCR5 in Autologous CD4...
SPCG-4 trial: Radical prostatectomy superior to watchful waiting
Image: PD 1. Radical prostatectomy for early, localized prostate cancer led to better overall survival compared to watchful waiting. 2. Radical prostatectomy had greatest mortality benefit...
