Radical prostatectomy significantly improves survival in localized prostate cancer: the SPCG-4 trial
1. Among men under 75 years of age with localized prostate cancer, radical prostatectomy was associated with a significant survival...
Urology
Reports of high-impact urology studies by medical professionals
Interpreting genetic variants in kidney and genitourinary disorders will likely require systematic curation of clinical variant databases
1. This secondary analysis of genetic data emphasized the high number of potentially “pathogenic” variants that are revealed through exome...
Quick Take: Surgery vs Radiotherapy in the Management of Biopsy Gleason Score 9-10 Prostate Cancer and the Risk of Mortality
Several treatment regimens are available for prostate cancer with a Gleason score of 9 or 10. These include radical prostatectomy...
Using HCV-infected kidneys greatly reduces wait time for transplantation and improves survival for patients with HCV
1. Use of HCV-infected kidneys increased patients’ quality-adjusted life expectancy. 2. Lower costs were associated with HCV-infected kidneys compared to...
Enzalutamide reduces risk of metastatic prostate cancer in at-risk men
1. Prostate cancer patients with a rapidly risking prostate-specific antigen (PSA) despite chemical or physical castration had lower rates of...
Nonsurgical treatment of small tumor renal cancer may be as effective as radical nephrectomy but with fewer complications
1. Rates of renal insufficiency were highest in patients receiving renal nephrectomy, compared to less invasive treatments. 2. Survival rates...
Postresection intravesical instillation of gemcitabine decreases non-muscle-invasive urothelial cancer recurrence
1. In this randomized controlled trial, time to recurrence was lower in patient with non-muscle-invasive urothelial cancer when treated with...
Coaching to improve water intake does not improve kidney function in adults with chronic kidney disease
1. In this randomized controlled trial, coaching to improve daily fluid intake did not improve kidney function in patients with...
Prediction tool for urinary tract infections in preverbal children
1. The study reports the development of a clinical and biochemical prediction tool for assessing the risk of urinary tract...
Optimizing organ donations from overdose deaths may help address national organ shortage
1. U.S. transplants using organs from overdose-death donors (ODDs) has increased 24-fold from 2000 to 2016, and transplant outcomes from...