Magnetic resonance imaging-targeted biopsy noninferior to standard biopsy for prostate cancer screening
1. Magnetic resonance imaging with targeted and standard biopsy was non-inferior for the detection of clinically significant cancers compared to standard biopsy only.
2. The...
7-day antibiotic therapy is noninferior to 14-day therapy in afebrile men with urinary tract...
1. A double-blinded, randomized controlled trial found that there were no significant differences between afebrile men treated for 7 days versus 14 days of...
Ipatasertib plus abiraterone significantly improves survival in patients with PTEN-negative prostate cancer compared to...
1. Ipatasertib-abiraterone treatment significantly improved progression-free survival compared to placebo-abiraterone in patients with PTEN-loss metastatic castration-resistant prostate cancer.
2. Grade 3 or greater adverse events...
Guideline-concordant multimodal therapy associated with improved mortality outcomes in patients with high-risk prostate cancer
1. Among patients with high-risk prostate cancer receiving guideline-concordant multimodal therapy, prostate cancer-specific mortality outcomes were equivalent among radical prostatectomy, external beam radiotherapy alone,...
Routine urinary tract cancer testing among all patients with microhematuria has low diagnostic yield
1. Evaluation with cystoscopy and CT urography for patients presenting with microhematuria (MH) had a low diagnostic yield for urinary tract cancers.
2. The diagnostic...
Enfortumab vedotin prolongs survival in previously treated advanced urothelial carcinoma
1. Enfortumab vedotin showed improved overall survival when compared to chemotherapy in patients with previously treated advanced urothelial carcinoma.
2. The incidence of serious adverse...
Tamsulosin therapy associated with significant reduction of symptoms of overactive bladder
1. Among men with symptoms of overactive bladder with or without concomitant benign prostatic hyperplasia, tamsulosin therapy significantly reduced the symptoms of overactive bladder.
Evidence...
Perioperative anticoagulation post robot-assisted radical prostatectomy not associated with increased high-grade bleeding risk
1. Patients continuing perioperative anticoagulation when undergoing robot-assisted radical prostatectomy did not experience an increased incidence of high-grade bleeding.
Evidence Level Rating: 2 (Good)
Robot-assisted radical...
Adjuvant radiotherapy may worsen outcomes compared to salvage radiotherapy post radical prostatectomy
1. Adjuvant radiotherapy was found to increase the risk of urinary incontinence and urethral strictures compared to salvage radiotherapy in patients with prostate cancer.
2....
Gastric bypass surgery more effective than medical therapy alone for achieving microalbuminuria remission in...
1. Patients who underwent Roux-en-Y gastric (RYGB) surgery had higher rates of microalbuminuria remission when compared to those who received only medical treatment at...
