Postresection intravesical instillation of gemcitabine decreases non-muscle-invasive urothelial cancer recurrence
1. In this randomized controlled trial, time to recurrence was lower in patient with non-muscle-invasive urothelial cancer when treated with intravesical gemcitabine as compared...
Coaching to improve water intake does not improve kidney function in adults with chronic...
1. In this randomized controlled trial, coaching to improve daily fluid intake did not improve kidney function in patients with Chronic Kidney Disease.
2. Increasing...
Prediction tool for urinary tract infections in preverbal children
1. The study reports the development of a clinical and biochemical prediction tool for assessing the risk of urinary tract infection in preverbal children...
Optimizing organ donations from overdose deaths may help address national organ shortage
1. U.S. transplants using organs from overdose-death donors (ODDs) has increased 24-fold from 2000 to 2016, and transplant outcomes from organs donated by ODDs...
Medicare pre-ESRD care results in more dialysis initiation but also increased two-year mortality
1. Veterans receiving pre-end stage renal disease (ESRD) nephrology care in under the Medicare system were more likely to undergo dialysis and had a...
Nivolumab plus ipilimumab improve survival in advanced renal cell carcinoma
1. Amongst patients with advanced renal-cell carcinoma and an intermediate or poor prognosis, nivolumab plus ipilimumab was superior to sunitinib alone in improving overall...
Single PSA screening increases prostate cancer detection but does not change mortality
1. In this randomized controlled trial, men who were screened with a single PSA test had higher diagnoses of prostate cancer than those who...
HCV-infected kidney donors could save lives
1. No HCV infection was detected in patients receiving HCV-infected kidneys 12 weeks following treatment.
2. No antiviral treatment-related complications occurred recipients of HCV-infected kidneys.
Evidence...
No effect of crystalloid type on in-hospital death and length of stay in non-critically...
1. Patients treated with either balanced crystalloids or normal saline did not differ in number of hospital-free days alive after their emergency department visit.
2....
Meropenem-vaborbactam non-inferior to piperacillin-tazobactam for complicated urinary tract infections: The TANGO I trial
1. In this randomized controlled trial, meropenem-vaborbactam was found to be non-inferior to piperacillin-tazobactam for treating complicated urinary tract infections (UTIs).
2. The rate of...
