Quick Take: Erdafitinib in locally advanced or metastatic urothelial carcinoma
Second-line single-agent chemotherapies or immune checkpoint inhibitors have provided suboptimal response rates and survival benefits in patients with locally advanced and unresectable or metastatic...
Quick Take: Image-guided Irreversible Electroporation of Localized Prostate Cancer: Functional and Oncologic Outcomes
There is a need for focal therapies for low to intermediate-risk prostate cancers, as whole-gland therapies have many complications without necessarily providing a survival...
Sodium-glucose cotransporter-2 inhibitors may be linked to Fournier gangrene
1. In this descriptive case series, 55 cases of patients with diabetes who developed Fournier gangrene while using sodium-glucose cotransporter-2 (SGLT2) inhibitors are described.
2....
Quick Take: Association of Domestic Responsibilities With Career Satisfaction for Physician Mothers in Procedural...
Although females currently account for roughly 50% of graduates from U.S. medical schools, there is a skew in terms of which residencies or medical...
Quick Take: Antibiotic management of urinary tract infection in elderly patients in primary care...
Urinary tract infection (UTI) is the most common bacterial infection in elderly patients, and the spectrum of illness ranges from mild and self-limiting to...
Study does not support use of low-dose aspirin after prostate cancer diagnosis
1. This study evaluated the effects of post-diagnosis low-dose aspirin on prostate cancer-specific mortality and found no overall benefit.
2. The study did find a...
Hypertension in adolescence associated with end-stage renal disease
1. In this retrospective cohort study from Israel, hypertension at the age of 16-19 years old was linked with later-life end stage renal disease...
Quick Take: Accelerated hypofractionated radiation therapy for elderly frail bladder cancer patients unfit for...
The standard of care for T2-T4aN0M0 muscle-invasive bladder cancer (MIBC) and high-risk non-MIBC in fit patients is radical cystectomy (RC). In patients unfit for...
Quick Take: Short-term androgen suppression and radiotherapy versus intermediate-term androgen suppression and radiotherapy, with...
The optimal duration of androgen suppression therapy with radiotherapy for locally advanced prostate cancer is unknown. In 2018, the French Canadian Prostate Cancer Study...
Radical prostatectomy significantly improves survival in localized prostate cancer: the SPCG-4 trial
1. Among men under 75 years of age with localized prostate cancer, radical prostatectomy was associated with a significant survival benefit compared to watchful...
