Casting only may be non-inferior to surgery for management of medial epicondyle fractures
1. Casting only was non-inferior compared to surgical treatment in the management of children with medial epicondyle fractures. Evidence Rating...
Pediatrics
Reports of high-impact pediatrics studies by medical professionals
Maternal hypertension associated with adverse neurodevelopment outcomes in preterm infants
1. Maternal hypertensive disorders of pregnancy (HDP) was independently associated with adverse cognitive and language outcomes at 2 years’ corrected...
Critical-care pain observation tool demonstrates reliability for critically ill pediatric patients
1. The Critical-Care Pain Observation Tool (CPOT) showed strong correlations with other validated pain observation tools in pediatric patients Evidence...
Epinephrine inferior to norepinephrine as initial treatment in children with septic shock
1. Epinephrine was associated with greater 30-day mortality compared to norepinephrine in the management of septic shock in pediatric patients....
Genomic sequencing identifies variants linked to congenital diarrhea and enteropathies
1. In this cross-sectional study, nearly half of the infants with congenital diarrhea and enteropathies (CODEs) had identifiable causal variants,...
Higher nicotine consumption observed among youth with attention-deficit hyperactivity disorder
1. This cohort of United States youths with asymptomatic attention-deficit hyperactivity disorder (ADHD), did not have statistically significant differences in...
Infigratinib shows promising efficacy and tolerability in pediatric achondroplasia
1. In this phase two dose-finding study in children with achondroplasia, daily oral Infigratinib did not lead to any grade...
Depemokimab therapy reduces exacerbations in patients with severe eosinophilic asthma
1. In this randomized, placebo-controlled replicate trial, depemokimab decreased the annual rate of exacerbations among patients with severe eosinophilic asthma....
Levofloxacin does not prevent infection in children exposed to MDR tuberculosis
1. In this randomized controlled trial, among children and adolescents with household exposure to an adult with multidrug-resistant tuberculosis, it...
Characterization of meconium-related obstruction and outcomes in term and preterm infants
Meconium-Related Obstruction and Clinical Outcomes in Term and Preterm Infants 1. Nearly 95% of cases of meconium-related obstruction (MRO) occur...
