• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Compression therapy may lower recurrent cellulitis in patients with chronic leg edema

byHarsh ShahandDeepti Shroff Karhade
August 22, 2020
in Chronic Disease, Infectious Disease
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Compression therapy significantly reduced the incidence of cellulitis recurrence for participants with leg edema and cellulitis compared to conservative management.

2. Compression therapy reduced edematous leg volume more effectively compared to education management.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Cellulitis is a bacterial infection of the skin and subcutaneous tissue with a high recurrence rate. One risk factor for recurrent cellulitis is chronic edema, where swelling persists for more than three months. Current prophylactic treatment for recurrent cellulitis is penicillin. However, nonantibiotic treatments have not been studied. As such, this study determined the efficacy of compression therapy to prevent cellulitis recurrence in participants with chronic leg edema, since the therapy has been shown to effectively control chronic leg edema. The results demonstrated that compression therapy significantly lowered cellulitis recurrence incidence for participants with chronic leg edema. This randomized trial was limited by its non-blinded study design. Nonetheless, this study was strengthened because it was the first to analyze a nonantibiotic treatment for cellulitis.

Click to read the study in NEJM

Relevant Reading: Effect of Dermatology Consultation on Outcomes for Patients with Presumed Cellulitis: A Randomized Clinical Trial

In-Depth [randomized controlled trial]: This randomized control trial enrolled 84 participants in a single-center study in Australia. Participants included in the study had a history of at least two episodes of cellulitis in the same leg and had chronic edema in either one or both legs. Participants younger than 18 years of age, who had received end-of-life care, had worn effective compression garments for more than five days per week, or had a chronic wound were excluded from this study. The patients were randomized in a 1:1 ratio to receive compression therapy plus cellulitis prevention education or cellulitis prevention education only. The primary outcome was cellulitis recurrence and follow-up ranged from 0 to 511 days with a median of 186 days. Specifically, the median follow-up time for the compression group was 209 days compared to the control group of 77 days. During the follow-up interviews, 88% of participants in the compression group had worn the garments at least four days per week, while 73% of the participants reported wearing the garments at least five days per week. Cellulitis recurrence occurred in 6 of 41 participants (15%) in the compression group compared to 17 of 43 participants (40%) in the control group (hazard ratio, 0.23; 95% confidence interval [CI] 0.09 to 0.59; P=0.002). In addition, hospital admission occurred for 3 participants (7%) in the compression group compared to 6 participants (14%) in the control group (hazard ratio, 0.38; 95% CI, 0.09 to 1.59). Furthermore, the mean leg volume for participants in the compression group was 181 mL less than at baseline compared to the mean leg volume for participants in the control group which increased by 60 mL (between-group difference in change, -241 mL; 95% CI, -365 to -117). Taken together, compression therapy along with cellulitis prevention education significantly lowered cellulitis recurrence incidence and reduced the leg volume compared to conservative management.

RELATED REPORTS

Early dermatology consultation linked to improved diagnostic accuracy and care in cellulitis

Patient Basics: Cellulitis

Dermatological consultation in outpatients improves diagnosis of cellulitis

Image: PD

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: cellulitiscompression therapy
Previous Post

Diet and gastric bypass have similar metabolic benefits in diabetic patients

Next Post

#VisualAbstract: The Portico aortic valve shows non-inferiority to commercially available valves (PORTICO IDE)

RelatedReports

Chronic Disease

Early dermatology consultation linked to improved diagnostic accuracy and care in cellulitis

February 28, 2018
Health A to Z

Patient Basics: Cellulitis

November 30, 2014
Dermatological consultation in outpatients improves diagnosis of cellulitis
Dermatology

Dermatological consultation in outpatients improves diagnosis of cellulitis

August 26, 2014
Next Post
#VisualAbstract: The Portico aortic valve shows non-inferiority to commercially available valves (PORTICO IDE)

#VisualAbstract: The Portico aortic valve shows non-inferiority to commercially available valves (PORTICO IDE)

2 Minute Medicine Rewind August 24, 2020

For-profit long term care homes associated with increased extent of COVID-19 outbreaks and related mortality

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Similar perinatal outcomes observed amongst conception via natural and assisted reproductive means
  • Combination doxycycline and azithromycin therapy effective in treating severe scrub typhus
  • Adenoma detection rate is inversely associated with post-colonoscopy colorectal cancer risk
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options