• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Emergency

Early changes over time in the Radiographic Assessment of Lung Edema (RALE) Score are associated with survival in acute respiratory distress syndrome

byBrian DoughertyandAlex Chan
July 15, 2020
in Emergency, Imaging and Intervention, Pulmonology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Among patients with ARDS, a reduction in RALE score in the first three days following onset was associated with decreased mortality at 90-days.

Evidence level Rating: 2 (Good)

The development of acute respiratory distress syndrome (ARDS) among critically ill patients portends significant morbidity and mortality. Non-invasive tests like the Radiographic Assessment of Lung Edema (RALE) score have been developed to characterize pulmonary edema in ARDS based on the extent and density of alveolar opacities seen on chest X-ray. The RALE score is based on the sum product of consolidation and density scores for each quadrant on imaging, with 48 being the maximal score. The purpose of this retrospective cohort study was to assess whether early changes in RALE score among patients with ARDS is associated with a decrease in 90-day mortality. Chest X-rays were available for 135 patients at baseline, 64 patients on day two, and 88 patients on day three. Of the 135 patients at baseline, 89 patients (mean [SD] age = 57 [15] years, 71% male) survived while 46 patients (mean [SD] age = 68 [14] years, 83% male) did not. It was found that baseline RALE score (HR for each one-point increment 1.04, 95% CI 1.01 to 1.08, p = 0.006) and the change in RALE score over time (HR for each one-point decrease in RALE score per unit of time 0.99, 95% CI, 0.99 to 0.99, p = 0.03) were independently associated with death at 90 days, even after adjusting for age, sex, BMI, vasopressor use, and total volume of fluids received. When comparing an absolute increase or no change in RALE score from baseline to day three to a decrease in RALE score over the same period, a higher risk of death at 90 days was observed (HR 3.39, 95% CI 1.14 to 10.09, p = 0.03). This study found that an early decrease in RALE score was associated with a decreased risk of mortality at 90 days among patients with ARDS. Such findings illustrate how serial chest X-ray imaging among such patients may be useful as a non-invasive prognostic marker of clinical outcomes.

Click to read the study in CHEST

Image: PD

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

RELATED REPORTS

Sodium-glucose cotransporter 2 inhibitors may decrease risk of serious liver events in patients with cirrhosis

#VisualAbstract: Lactated Ringer’s Solution Does Not Improve Outcomes Relative to Normal Saline

2MM: AI Roundup – FDA’s AI Push, Trial Speedups with Real-World Data, Smart Surgical Monitors, and Regulatory Overhaul Begins [July 2nd, 2025]

Previous Post

2 Minute Medicine Rewind July 13, 2020

Next Post

Greater frequency of laughter linked to decreased stress symptoms

RelatedReports

Low free sugar diet reduces hepatic steatosis in nonalcoholic fatty liver disease in adolescent males
Chronic Disease

Sodium-glucose cotransporter 2 inhibitors may decrease risk of serious liver events in patients with cirrhosis

July 2, 2025
#VisualAbstract: Lactated Ringer’s Solution Does Not Improve Outcomes Relative to Normal Saline
StudyGraphics

#VisualAbstract: Lactated Ringer’s Solution Does Not Improve Outcomes Relative to Normal Saline

July 2, 2025
2MM: AI Roundup- AI Cancer Test, Smarter Hospitals, Faster Drug Discovery, and Mental Health Tech [May 2nd, 2025]
AI Roundup

2MM: AI Roundup – FDA’s AI Push, Trial Speedups with Real-World Data, Smart Surgical Monitors, and Regulatory Overhaul Begins [July 2nd, 2025]

July 2, 2025
The Scan by 2 Minute Medicine®:  Ultra-Trail du Mont-Blanc, Taylor Swift, NBA rookie Chet Holmgren and Magic Mushrooms!
The Scan by 2 Minute Medicine®

The Scan by 2 Minute Medicine®: Celebrity diagnoses spur screenings, athlete mental-health push, reality-TV heart lesson, and a sitcom PSA wave

July 2, 2025
Next Post
Galcanezumab reduces the frequency of episodic cluster headaches

Greater frequency of laughter linked to decreased stress symptoms

Early changes over time in the Radiographic Assessment of Lung Edema (RALE) Score are associated with survival in acute respiratory distress syndrome

Early changes over time in the Radiographic Assessment of Lung Edema (RALE) Score are associated with survival in acute respiratory distress syndrome

Natural language processing may automate data extraction from radiologic reports

Providers require additional support with telehealth visits during the pandemic

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Sodium-glucose cotransporter 2 inhibitors may decrease risk of serious liver events in patients with cirrhosis
  • #VisualAbstract: Lactated Ringer’s Solution Does Not Improve Outcomes Relative to Normal Saline
  • 2MM: AI Roundup – FDA’s AI Push, Trial Speedups with Real-World Data, Smart Surgical Monitors, and Regulatory Overhaul Begins [July 2nd, 2025]
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.