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Home All Specialties Chronic Disease

Ethnic disparities in HPV 16/18-positive high-grade cervical lesions

bys25qthea
May 11, 2013
in Chronic Disease, Infectious Disease, Obstetrics, Public Health
Reading Time: 3 mins read
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Image: PD

1. Among women with high-grade cervical lesions, black and Hispanic women were less likely to have human papillomavirus (HPV) types 16/18 than white women. 

2. Women residing in poor areas were less likely to have HPV 16/18-positive lesions than women in wealthier areas. 

Evidence Rating Level: 2 (Good) 

Study Rundown: Among women with high-grade cervical lesions, women who were black, Hispanic, or resided in a poor area were less likely to have HPV 16/18-positive lesions. These results suggest that current HPV vaccination would not decrease the risk of high-grade cervical lesions in these populations. Strengths of this study were inclusion of individual and geographically based demographic data and case identification through a mandatory statewide surveillance program. However, only 45% of cases were eligible for inclusion, primarily due to lack of DNA testing (HPV typing) of high-grade lesions, which could limit generalizability. Additional investigations might examine HPV types in high-grade lesions in black and Hispanic women to inform vaccine development research.

Click to read the study in Cancer

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Relevant Reading: Geographic poverty and racial/ethnic disparities in cervical cancer precursor rates in Connecticut, 2008-2009

In-Depth [retrospective cohort study]: This study examined the prevalence of HPV 16/18 in high-grade cervical lesions among 832 Connecticut women (ages 18-39) who had never received HPV vaccines. Eligible cases were reported between 2008 and 2010 and received HPV DNA testing. Data on race/ethnicity, health insurance status, age, type of lesion, and area of residence were obtained from medical records and patient interviews.

Among women with high-grade lesions, black and Hispanic women were less likely than white women to have HPV 16/18 (both p=0.01). Additionally, women residing in areas with ≥20% poverty were less likely to have HPV 16/18 than women in areas with <20% poverty (p=0.007). Younger age and higher grade lesions were associated with higher prevalence of HPV 16/18-positive lesions, though insurance status was not.

By Caroline Huang and Leah Hawkins

More from this author: Exercise program does not reduce depression in the elderly, Integrated 2D/3D mammography improves breast cancer detection, One third of breast cancer survivors report pain 5-7 years after treatment, Varenicline reduces post-quit smoking relapses, Severe maternal childhood abuse associated with autism in offspring

© 2013 2minutemedicine.com. All rights reserved. No works may be reproduced without written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT. Content is produced in accordance with fair use copyrights solely and strictly for the purpose of teaching, news and criticism. No benefit, monetary or otherwise, is realized by any participants or the owner of this domain. 

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