ICD-10-CM code · FY2027
F11.21 Opioid dependence, in remission
BillableValid for claims as a specific diagnosis code
About F11.21
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Coding notes for F11.21
Applicable to Other names for conditions reported with this code.
- Opioid use disorder, moderate, in early remission
- Opioid use disorder, moderate, in sustained remission
- Opioid use disorder, severe, in early remission
- Opioid use disorder, severe, in sustained remission
Also applies, from F11.2 Opioid dependence
Excludes1 Not coded here: never report these together with this code (use the code given instead).
Excludes2 Not part of this condition, but a patient can have both: report both codes when both apply.
Chapter 5 notes (apply to every code in it)
Includes Conditions this code covers.
- disorders of psychological development
Related codes in F11.2
- F11.20 Opioid dependence, uncomplicatedBillable
- F11.22 Opioid dependence with intoxicationHeader
- F11.23 Opioid dependence with withdrawalBillable
- F11.24 Opioid dependence with opioid-induced mood disorderBillable
- F11.25 Opioid dependence with opioid-induced psychotic disorderHeader
- F11.28 Opioid dependence with other opioid-induced disorderHeader
- F11.29 Opioid dependence with unspecified opioid-induced disorderBillable
Latest research on opioid use disorder
- Behavioral support does not improve patient-directed opioid tapering success
- Rising amputation rates, especially among opioid-related hospitalizations
- Evidence gap for acute pain outcomes in opioid use disorder
- Vertex: non-opioid pain reliever Journavx shows success in post operative pain control
- #VisualAbstract: Methadone is a Better Treatment for Opioid Use Disorder than Buprenorphine/Naloxone
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See 2MM+ plansICD-10-CM FY2027 code set, as published by the CDC National Center for Health Statistics (NCHS) and CMS, effective October 1, 2026 to September 30, 2027. Codes, titles and notes are shown as published. Check payer rules and the official guidelines before billing. This page is not medical advice.
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