• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Low familiarity of guideline-directed heart failure care among patients

byJames EnglandandAnees Daud
November 25, 2019
in Cardiology, Public Health
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. In this survey of patients with heart failure, most participants were familiar with angiotensin-converting enzyme inhibitors (ACE-I), angiotensin receptor blockers (ARB), beta-blockers and diuretics. Fewer patients reported familiarity with angiotensin receptor–neprilysin inhibitors or mineralocorticoid receptor antagonists.

2. Patients commonly reported concerns with regards to the safety profile and effectiveness of medications included in guideline-directed therapy.

Evidence Rating Level: 3 (Average)       

Study Rundown: Heart failure is a common chronic medical condition with significant mortality, morbidity, and reduction in quality of life. Use of pharmacologic strategies have led to reductions in heart failure symptoms, hospital admissions, and improved mortality. Guidelines suggesting the optimal combination therapies and adequate dosing of these medications are often not followed. The current study sought to evaluate the pharmacotherapy knowledge of patients with chronic heart failure, to explore if this may affect the likelihood of adhering to guideline-directed medical therapy (GDMT). The study found that most patients were familiar with beta-blockers, diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and less commonly knowledgeable of angiotensin receptor–neprilysin inhibitors or mineralocorticoid receptor antagonists. Many patients reported concerns with regards to efficacy and safety profiles of these medications.

The current study highlights the importance of patient education and the need to further inform patients on the options and evidence for GDMT. The main strength of the study is the large contemporary cohort of heart failure patients exploring patient values and perceptions of therapy. The main weaknesses of the study is selection bias for participants with fairly high education levels, and lack of patient knowledge over factors that may influence therapy choice (such as ejection fraction).

Click to read the study in JAMA Cardiology

Relevant Reading: Patient activation, knowledge, and health literacy association with self-management behaviors in persons with heart failure

RELATED REPORTS

Dapagliflozin efficacious and safe in treating heart failure

Interatrial shunt device not effective in patients with symptomatic heart failure

#VisualAbstract: Effectiveness of sacubitril-valsartan in post-myocardial infarction management compared to ramipril

In-Depth [survey]: This study used data from the GfK Knowledge Panel, a probability-based online panel designed to be representative of the noninstitutionalized civilian American population. Participants were included if they were 18 years or older, self-reported a heart failure diagnosis, and were taking heart failure medications. Patients with a left-ventricular assist device or heart transplant were excluded. Data was collected from October to November 2018.

The study included 429 participants who completed the survey, with most (409 [95.3%]) having at least a high school education. Most respondents were familiar with beta-blockers (354[82.5%]), ACE-I or ARB (322 [75.2%]), and diuretics (339 [79.1%]); while fewer knew about angiotensin receptor–neprilysin inhibitors (105 [24.6%]) and mineralocorticoid receptor antagonists 94 (22.4%). Patients frequently reported concerns of safety (36.5-41.5%) and efficacy (27.7%-41%).

Image: PD

©2019 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: angiotensin receptor-neprilysin inhibitorgoal directed medical therapyheart failuremineralocorticoid receptor antagonists
Previous Post

2 Minute Medicine Rewind November 25, 2019

Next Post

Overall childhood injuries from nonpowder firearms are decreasing, eye injuries are increasing

RelatedReports

Radiation dose associated with increased heart disease in Hodgkin lymphoma survivors
Cardiology

Dapagliflozin efficacious and safe in treating heart failure

May 13, 2022
30-Day mortality decreased in UK pediatric cardiac surgery from 2000-2010
Cardiology

Interatrial shunt device not effective in patients with symptomatic heart failure

March 29, 2022
StudyGraphics

#VisualAbstract: Effectiveness of sacubitril-valsartan in post-myocardial infarction management compared to ramipril

February 10, 2022
Cardiology

Sacubitril or valsartan versus standard medical therapies in patients with heart failure with preserved ejection fraction: PARALLAX trial

November 17, 2021
Next Post
Meeting families, demographic information affect child abuse work-up

Overall childhood injuries from nonpowder firearms are decreasing, eye injuries are increasing

Quick Take: Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial

Lower LDL cholesterol level after ischemic stroke decreases risk of subsequent stroke

Long-term outcomes for off-pump and on-pump CABG are similar

Daily colchicine after myocardial infarction lowers risk of subsequent event

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Gratitude-focused writing may improve mental wellness during periods of chronic stress
  • Adebrelimab plus chemotherapy improves overall survival in extensive-stage small-cell lung cancer
  • Tiragolumab with atezolizumab is a promising treatment option for PD-L1 positive advanced non-small-cell-lung cancer
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.