• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Imaging and Intervention

MR lymphangiography useful for evaluation of central lymphatic pathology

byDylan WolmanandAaron Maxwell, MD
October 20, 2014
in Imaging and Intervention, Oncology
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

 1. In this proof-of-concept study, central thoracic magnetic resonance lymphangiography (MRL) was successfully used to characterize the presence or absence of disease within the central lymphatic vessels in a small series of patients.

Evidence Rating Level: 4 (Below Average)

Study Rundown: Lymphatic pathology, whether congenital or acquired, can lead to lymphedema, chylothorax, or other chylous fluid collections that may be difficult to diagnose and treat without adequate evaluation of the associated lymphatic anatomy. Assessment of this anatomy by direct contrast injection has typically been limited to the extremities, as in procedures such as sentinel node mapping or intradermal lymphoscintigraphy. These methods do not adequately opacify larger, central lymphatics such as the thoracic duct or cisterna chyli; however, and alternative imaging modalities such as routine T2-weighted magnetic resonance (MR) imaging fail to capture information regarding dynamic flow. In the current study, a temporally-sequenced MR-based imaging technique was used to evaluate the central lymphatic vascular tree in a small series of patients with symptoms concerning for lymphatic disease. The technique successfully visualized the relevant lymphatic structures in all evaluated subjects and allowed for appropriate management steps to be undertaken in each case. The study was limited by its small sample size and lack of a reference standard. Procedurally, the technique was limited by its labor-intensive and invasive requirements, such as the need for endotracheal intubation to achieve adequate breath holding during image acquisition. Future studies directly comparing T2-weighted lymphatic MR imaging to contrast-enhanced MRL are needed to better assess the added value of this new technique.

Click to the read the study in Radiology

Relevant Reading: MRI of lymphatic abnormalities after functional single-ventricle palliation surgery

In-Depth [retrospective case series]: Six consecutive patients with a clinical indication for central conducting lymphatic imaging were retrospectively selected for evaluation after undergoing dynamic T1-weighted MRL with gadolinium-based contrast. Gadopentetate dimeglumine was infused into the medulla of inguinal lymph nodes at a concentration of 0.2mmol/kg by direct cannulation. All patients required intubation, sedation, and mechanical ventilation to facilitate breath holding for adequate image acquisition. Images were acquired every 30-60 seconds as the contrast traveled through the retroperitoneal lymphatics into the cisterna chyli and thoracic duct. This process was technically successful in all patients, and all associated MR images were of diagnostic quality. Overall, MRL positively identified lymphatic disease in 4 of 6 patients and excluded lymphatic disease in the remaining 2 patients. Clinically, MRL changed management for 2 patients in whom previously-unknown lymphatic dysplasia was diagnosed, while conservative management was subsequently pursued for 3 patients in whom normal anatomy, chylolymphatic reflux, or expected post-surgical changes were identified. The final patient was revealed to be suffering from non-lymphatic pathology. No adverse events were identified in this study.

More from this author: MRI may predict progression to early dementia in healthy elderly adults, Preoperative MRI improves surgical outcomes in robotic prostatectomy, Many lung cancers visible on prior imaging studies.

RELATED REPORTS

The Scan by 2 Minute Medicine®: the Future of Medicine, Neuralink, the Spotlight on Celine Dion and COVID-19 on Social Media

Development and validation of a prediction model to estimate ascending aorta diameter in asymptomatic individuals

PI-RADS version 2: Standardized acquisition, interpretation, and reporting of prostate MRI [Classics Series]

Image: PD

©2012-2014 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT. 

 

Tags: lymphaticsmri
Previous Post

Twin-specific gestational diabetes screening guidelines needed

Next Post

VEGFR-targeted ultrasound may improve detection of pancreatic cancer

RelatedReports

The Scan by 2 Minute Medicine®:  Ultra-Trail du Mont-Blanc, Taylor Swift, NBA rookie Chet Holmgren and Magic Mushrooms!
The Scan by 2 Minute Medicine®

The Scan by 2 Minute Medicine®: the Future of Medicine, Neuralink, the Spotlight on Celine Dion and COVID-19 on Social Media

December 27, 2022
Endovascular repair of ruptured AAAs no better than open repair
Cardiology

Development and validation of a prediction model to estimate ascending aorta diameter in asymptomatic individuals

November 17, 2022
The ABCD2 score: Risk of stroke after Transient Ischemic Attack (TIA) [Classics Series]
Radiology Classics

PI-RADS version 2: Standardized acquisition, interpretation, and reporting of prostate MRI [Classics Series]

August 16, 2022
The ABCD2 score: Risk of stroke after Transient Ischemic Attack (TIA) [Classics Series]
Radiology Classics

MRI offers an alternative to endoscopic assessment of disease activity and severity in ileocolonic Crohn’s disease [Classics Series]

August 11, 2022
Next Post
VEGFR-targeted ultrasound may improve detection of pancreatic cancer

VEGFR-targeted ultrasound may improve detection of pancreatic cancer

Severe psoriasis linked with poorly controlled blood pressure

Severe psoriasis linked with poorly controlled blood pressure

Incidence of esophageal cancer subtypes vary drastically globally and by gender

Incidence of esophageal cancer subtypes vary drastically globally and by gender

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • BNT162b2 booster is safe and reduces COVID-19 transmission in older adults
  • Bisphosphonates, denosumab, abaloparatide, teriparatide, and romosozumab reduce postmenopausal fracture risk
  • Epstein-Barr viral load monitoring reduces risk of post-liver transplant lymphoproliferative disease
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options