• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

No long-term cognitive benefits observed with daily multivitamin usage

bys25qthea
December 18, 2013
in Chronic Disease, Neurology
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

Image: PD

1. In male physicians aged greater than 65 years old, no mean difference in cognition was observed between multivitamin and placebo groups. 

Evidence Rating Level: 1 (Excellent)       

Study Rundown: Cognitive decline is a common pathology that arises with aging, and it is associated with significant morbidity and mortality. The evidence for the role of multivitamins in preventing cognitive decline is sparse and inconsistent. This study is one of the first large long-term clinical trials to examine the relationship of daily multivitamins and the potential protective effects on cognitive decline.  The study included male physicians aged >65 years old.  Participants were randomized into groups that were characterized by active and placebo combinations of beta-carotene, vitamin C, vitamin E and/or multivitamin. Patient follow-up occurred for up to 14 years and included 4 cognitive assessments. Results failed to show a statistically significant difference in cognitive scores or verbal memory between the treatment groups. The major limitation of the trial arises from its study population, which included only male physicians.  First, this population is more likely to be well nourished and highly educated.  Especially given that education is known to be protective against cognitive decline, the potential benefit may be less in this group compared to the general population.  Furthermore, this data cannot be generalized to woman as they may have different nutritional needs.  Nevertheless, the strengths of this study include its robust study design, long-term follow up and large population size.

Click to read the study in the Annals of Internal Medicine

Relevant Reading: Multivitamins in the prevention of cancer in men: the Physicians’ Health Study II randomized controlled trial

In-Depth [randomized controlled trial]: This study enrolled 5947 male physicians aged 65 years or older. The trial was run as a 2 X 2 X 2 X 2 factorial trial – patients once accepted were randomized into 4 separate active or placebo vitamin groups until there were 16 separate groups with different characteristics. Outcomes were measured by composite scores of common cognitive tests reflecting global cognition, verbal memory, and category fluency. Verbal memory score – a strong predictor of Alzheimer’s disease – also was used as a secondary outcome. It was found that cognitive function did not change significantly throughout the follow-up period between multivitamin and placebo group -0.01 SU [CI95% -0.04 – 0.02] for the global cognitive score. Verbal memory score also showed no difference over the follow-up period -0.005 SU [CI95% -0.04 – 0.03].

RELATED REPORTS

Higher body mass index may be associated with altered vitamin D levels and metabolism

Plant-based diets may be associated with lower risk of aggressive prostate cancer

Wellness Check: Nutrition

By Adam Whittington and Aimee Li, MD

More from this author: Home-based intervention reduces depressive symptoms in older African Americans, Self-measured blood pressure monitoring lowers pressures compared to typical clinical monitoring, Insufficient data for screening asymptomatic adults with ankle-brachial index, Arsenic exposure linked with cardiovascular disease and mortality

©2012-2013 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT.  

Tags: nutritionsupplements
Previous Post

Early TIPS in cirrhosis and variceal bleeding [Classics Series]

Next Post

Intranasal oxytocin may improve sociocommunicational deficits in autism

RelatedReports

Sleep duration inversely related to childhood type 2 diabetes risk makers
Chronic Disease

Higher body mass index may be associated with altered vitamin D levels and metabolism

January 27, 2023
Vegetarian diet may lower incidence of colorectal cancer
Lifestyle

Plant-based diets may be associated with lower risk of aggressive prostate cancer

January 27, 2023
Improved glycemic control in type 1 diabetics on very low-carbohydrate diets
Wellness

Wellness Check: Nutrition

January 26, 2023
FDA-approved weight loss medications associated with weight loss at one year
Chronic Disease

Christian Orthodox Church fasting may improve metabolic syndrome risk factors

January 6, 2023
Next Post
Severe maternal childhood abuse associated with autism in offspring

Intranasal oxytocin may improve sociocommunicational deficits in autism

SSRI use during pregnancy not linked to increased risk of autism

SSRI use during pregnancy not linked to increased risk of autism

Influenza vaccine associated with lower risk of major cardiovascular events

Quadrivalent influenza vaccine efficacious in children

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Higher body mass index may be associated with altered vitamin D levels and metabolism
  • #VisualAbstract: Torsemide does not provide additional decrease in mortality compared to furosemide among patients hospitalized for heart failure
  • Community-based adult vision screening program increases access to eye care
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options