• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Quick Take: Association of Childhood-Onset Inflammatory Bowel Disease With Risk of Psychiatric Disorders and Suicide Attempt

byDonna LeetandAliya Ramjaun
September 5, 2019
in Chronic Disease, Gastroenterology, Pediatrics, Psychiatry
Reading Time: 2 mins read
1
Share on FacebookShare on Twitter

RELATED REPORTS

Childhood maltreatment may cause mental health problems

Wellness Check: Mental Health

Spirituality may promote mental health recovery for people with schizophrenia in Southeast Asia

Childhood-onset inflammatory bowel disease (IBD) typically has a more severe course than adult-onset IBD, and has been found to be associated with psychiatric morbidity in previous studies. However, these studies have failed to account for familial confounding. In this population-based cohort study, 6,464 patients with childhood-onset IBD were compared with 323,200 matched controls and 6,999 siblings of patients with IBD to examine the risk of psychiatric morbidity, including any psychiatric disorder and suicide attempt. At baseline, 3,228 patients had ulcerative colitis, 2,536 had Crohn’s disease, and 700 had IBD-unclassified. Patients were followed for a median of 9 years (IQR 4 to 15 years), and the median age at the end of follow-up was 23 years (IQR 18 to 29 years). Researchers found that, during the follow-up period, more patients with childhood-onset IBD received a diagnosis of any psychiatric disorder (incidence rate (IR) 17.1 per 1,000 person-years) than matched controls (IR 11.2 per 1,000 person-years, HR 1.6, 95% CI 1.5 to 1.7). Moreover, more patients with childhood-onset IBD attempted suicide (IR 1.6 per 1,000 person-years) than matched controls (IR 1.2 per 1,000 person years, HR 1.4, 95% CI 1.2 to 1.7). Childhood-onset IBD was also associated with mood disorders (HR 1.6, 95% CI 1.4 to 1.7), anxiety disorders (HR 1.9, 95% CI 1.7 to 2.0), eating disorders (HR 1.6, 95% CI 1.3 to 2.0), personality disorders (HR 1.4, 95% CI 1.1 to 1.8), attention-deficit/hyperactivity disorder (HR 1.2, 95% CI 1.1 to 1.4), and autism spectrum disorders (HR 1.4, 95% CI 1.1 to 1.7). The sibling comparison confirmed the observed associations, and results were similar between girls and boys. The risk of any psychiatric disorder was tripled in the first year after IBD diagnosis (HR 3.5, 95% CI 3.0 to 4.0) and remained statistically significant after 5 or more years of follow-up (HR 1.3, 95% CI 1.2 to 1.5). Finally, there was a particularly increased risk of any psychiatric disorder among patients with very early-onset IBD (<6 years of age, HR 2.4, 95% CI 1.9 to 3.1), as well as those with extra-intestinal manifestations (HR 2.0, 95% CI 1.7 to 2.4), bowel surgery (HR 1.9, 95% CI 1.6 to 2.2), perianal surgery (HR 2.0, 95% CI 1.7 to 2.4), and parental psychiatric history (HR 3.4, 95% CI 1.7 to 6.7) as compared to matched controls. This study was limited by a lack direct measurement of IBD severity. In summary, this study emphasizes the increased risk of psychiatric morbidity in patients with childhood-onset IBD, and thus, the critical importance of mental health surveillance in this patient group.

Click to read the study JAMA Pediatrics

Image: PD

©2019 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: anxietyinflammatory bowel disease (IBD)mental healthmood disordersuicide
Previous Post

#VisualAbstract: Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

Next Post

Decrease in admissions, testing of patients with brief resolved unexplained events

RelatedReports

Multiple factors may increase risk of falls in young children
Pediatrics

Childhood maltreatment may cause mental health problems

March 31, 2023
Quick Take: Prevalence and Treatment of Depression, Anxiety, and Conduct Problems in US Children
Wellness

Wellness Check: Mental Health

March 30, 2023
Palliative care consultation linked to lower deaths by failed code resuscitation
Psychiatry

Spirituality may promote mental health recovery for people with schizophrenia in Southeast Asia

March 24, 2023
High incidence of cognitive impairment associated with colorectal cancer
Wellness

Wellness Check: Spirituality

March 23, 2023
Next Post
Behavioral dysregulation in infancy predicts later child mental health

Decrease in admissions, testing of patients with brief resolved unexplained events

Brain lesions on MRI linked with subsequent increased stroke risk

Quick Take: Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis

Pre-exposure prophylaxis (PrEP) effective in preventing HIV infection in high-risk gay men

The NAMSAL ANRS 12313 trial: HIV viral suppression similar for dolutegravir and low-dose efavirenz treatment

Please login to join discussion

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Addition of fludrocortisone to hydrocortisone is beneficial in management of septic shock
  • Surveillance testing of staff at nursing facilities reduces resident COVID-19 mortality
  • Childhood maltreatment may cause mental health problems
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options