Tag: inflammatory bowel disease (IBD)

1. At weeks 10 and 58, more patients in the filgotinib 200 mg group experienced clinical remission compared with the placebo group. 2. The proportion of patients with treatment-related side effects was similar between filgotinib 100 mg, filgotinib 200 mg, and placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Ulcerative colitis (UC)...

1. In children with chronic, non-bloody diarrhea and abdominal pain, a clinical prediction tool using symptoms, C-reactive protein (CRP), hemoglobin, and fecal calprotectin accurately predicted the presence or absence of inflammatory bowel disease (IBD). 2. This strategy may be helpful in reducing the number of unnecessary endoscopies for children with...

Childhood-onset inflammatory bowel disease (IBD) typically has a more severe course than adult-onset IBD, and has been found to be associated with psychiatric morbidity in previous studies. However, these studies have failed to account for familial confounding. In this population-based cohort study, 6,464 patients with childhood-onset IBD were compared...

Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis Diagnosing multiple sclerosis (MS) is challenging, in part because imaging findings in MS partially overlap with MS mimics such as vascular disease, migraine, and neuromyelitis optica spectrum disorder (NMOSD). The central vein sign has been shown...