• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Individuals with autoimmune diseases may have an increased risk for cardiovascular diseases

byJessie WillisandTeddy Guo
September 14, 2022
in Cardiology, Chronic Disease, Endocrinology, Rheumatology
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. An increased incidence of new cardiovascular disease was seen in individuals with autoimmune disease compared to those without.

2. This increased risk was greatest in younger patients and increased among patients with multiple autoimmune conditions.

Evidence Rating Level: 2 (Good)

Study Rundown: Autoimmune diseases are known to be associated with cardiovascular disease. This large longitudinal study aimed to evaluate the association between common autoimmune disease and cardiovascular outcomes. Using electronic health records, the study identified individuals with incident autoimmune conditions within a 17-year period. For each included individual, the study identified multiple matched comparison patients. After a median follow-up period of 6.2 years, cardiovascular disease developed in 15.5% of individuals in the autoimmune cohort compared to 11.0% of individuals in the comparison cohort. The risk of cardiovascular disease increased with the number of autoimmune conditions an individual was diagnosed with. The risk was additionally higher in younger patients and those with specific autoimmune conditions, such as systemic sclerosis or Addison’s disease. Limitations of this study include the inability to control for important confounding variables such as patient medications or pre-existing risk of cardiovascular disease, including family history. Nevertheless, this study identified important populations for preventive health planning, such as younger patients with autoimmune disease.

Click to read the study in the Lancet

Relevant Reading: Rheumatoid Arthritis and Incidence of Twelve Initial Presentations of Cardiovascular Disease: A Population Record-Linkage Cohort Study in England

In-Depth [prospective cohort]: This study assembled a cohort of individuals from an electronic health database who were registered between January 1, 2000, to June 30, 2019. From this general population cohort, the study further identified patients with an incident autoimmune disease (from a list of 19 conditions) between January 1, 2000, to December 31, 2017. Eligible participants were younger than 80 years at diagnosis and must have been free of cardiovascular disease until 12 months after the incident autoimmune disease. To avoid including patients with prior autoimmune disease, patients were excluded if they had autoimmune diagnoses prior to January 1, 2000, or within the first 12 months of registration. A randomly selected comparison group was created with individuals matched on age, calendar time, sex, socioeconomic status, and region. The primary endpoint was the presentation of cardiovascular disease (from a list of 12 conditions). A total of 446 449 patients were included in the autoimmune disease cohort with a mean age at diagnosis of 46.2 years and 60.8% being women. There were 2 102 830 individuals in the matched cohort. Incident cardiovascular disease developed in 68 413 (15.5%) of individuals in the autoimmune cohort compared to 231 410 (11.0%) in the comparison group during a median follow-up period of 6.2 years. The incidence rate for cardiovascular disease was greater in patients with autoimmune disease compared to those without (HR 1.56 [95% CI 1.52-1.59]). The risk of cardiovascular disease additionally increased with an increasing number of autoimmune conditions (one disease: HR 1.41; two diseases: 2.63; three or more diseases: 3.79). The risk was higher in younger patients and with specific conditions such as systemic sclerosis, Addison’s disease, systemic lupus erythematosus, and type 1 diabetes.

RELATED REPORTS

Catheter ablation reduces rates of persistent atrial fibrillation and atrial tachyarrhythmia

Empagliflozin use is associated with slower progression of chronic kidney disease

Bimekizumab is effective for active psoriatic arthritis in biologic-naĂŻve adults

Image: PD

©2022 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: Addison's diseaseautoimmuneautoimmune diseasecardiologycardiovascular diseaseCrohn's Diseaseinfective endocarditisinflammatory bowel disease (IBD)MyocarditispericarditisPeripheral Arterial Diseaserheumatoid arthritisrheumatologysystemic lupus erythematosussystemic lupus erythematosus (SLE)systemic sclerosisType 1 Diabetes MellitusUlcerative Colitis
Previous Post

The OVIVA trial: Oral versus intravenous antibiotics for bone and joint infection [Classics Series]

Next Post

Artificial sweetener intake and association with cardiovascular disease risk

RelatedReports

β-blockers linked to improved survival in preserved ejection fraction heart failure
Cardiology

Catheter ablation reduces rates of persistent atrial fibrillation and atrial tachyarrhythmia

January 27, 2023
Fish oil and aspirin did not reduce arteriovenous fistula failure: The FAVOURED trail
Cardiology

Empagliflozin use is associated with slower progression of chronic kidney disease

January 26, 2023
Long-term use of apremilast for psoriasis associated with an acceptable safety profile
Chronic Disease

Bimekizumab is effective for active psoriatic arthritis in biologic-naĂŻve adults

January 24, 2023
Remote patient monitoring did not reduce heart failure readmissions: The BEAT-HF trial
Cardiology

Clinical decision-making strategy improves acute heart failure outcomes

January 12, 2023
Next Post
Significant amount of unhealthy children’s foods marketed to parents

Artificial sweetener intake and association with cardiovascular disease risk

Paternal factors associated with short interpregnancy interval

Machine learning tools to predict threatened miscarriage in first trimester

#VisualAbstract: Functional testing nonsuperior to routine care for percutaneous coronary intervention patients

#VisualAbstract: Screening patients with atrial fibrillation with an implantable loop recorder does not decrease the incidence of subsequent stroke

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Higher body mass index may be associated with altered vitamin D levels and metabolism
  • #VisualAbstract: Torsemide does not provide additional decrease in mortality compared to furosemide among patients hospitalized for heart failure
  • Community-based adult vision screening program increases access to eye care
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options