Tag: Type 1 Diabetes Mellitus

1. Time in range after 6 months was higher with rtCGM than with isCGM. 2. Participants on rtCGM scored better on the satisfaction subscale of the Diabetes Treatment Satisfaction Questionnaire status (mean difference of 2.34 points). Evidence Rating Level: 1 (Excellent) Study Rundown: Progress in the field of home glucose monitoring systems...
1. Participants using the novel advanced hybrid insulin delivery system (Medtronic) had a greater proportion of time spent in their target glucose range versus control. 2. Proportion of time spent in hypoglycemic ranges was non-inferior between the Medtronic and control groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Although various technological advances...
1. Participants using the novel advanced hybrid insulin delivery system (Medtronic) had a greater proportion of time spent in their target glucose range versus control. 2. Proportion of time spent in hypoglycemic ranges was non-inferior between the Medtronic and control groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Although various technological advances...
1. The closed-loop system maintained glucose levels within the target range for a significantly greater percentage of time for children with type 1 diabetes. 2. More adverse events were reported with use of the closed-loop system. Evidence Rating Level: 1 (Excellent) Study Rundown: The target glycated hemoglobin level is difficult to maintain...
1. Patients who used continuous glucose monitoring (CGM) showed significantly reduced glycated hemoglobin (HbA1C) levels compared to those who used standard blood glucose monitoring (BGM) after 26 weeks. 2. On average, patients in the CGM group spent more time in the target glucose range (70-180 mg/dL) compared to those in...
Intensive glycemic control has been shown to reduce the risk of retinopathy and nephropathy in the setting of type 1 diabetes. While prior studies have established that an elevated hemoglobin A1C (HbA1C) is an independent risk factor for diabetic complications, few studies have followed patients from the time of...
1. In relatives of patients with type 1 diabetes (T1DM) at risk for disease development, randomization to teplizumab delayed time to T1DM diagnosis compared to placebo treated patients. 2. Adverse events associated with teplizumab treatment included rash and transient lymphopenia. Evidence Rating Level: 1 (Excellent)   Study Rundown: T1DM results from autoimmune destruction...
Type 1 diabetes (T1D) is thought to result from a combination of genetic and environmental factors. An increased intake of dietary fiber and gluten has been hypothesized to contribute to the development of T1D, though supporting data is scarce. In this cohort study, 6,081 infants with human leukocyte antigen...
Pregnancy duration and endometrial cancer risk: nationwide cohort study Full-term pregnancies are strongly associated with a reduced risk of endometrial cancer. Whether this protective association is driven by fecundity, a specific process that occurs during pregnancy, or cumulative number of months pregnancy, however, is unknown. In this cohort study, 2,311,332...
1. In relatives of patients with type 1 diabetes (T1DM) at risk for disease development, randomization to teplizumab delayed time to T1DM diagnosis compared to placebo treated patients. 2. Adverse events associated with teplizumab treatment included rash and transient lymphopenia. Evidence Rating Level: 1 (Excellent)   Study Rundown: T1DM results from autoimmune...