Tag: systemic lupus erythematosus (SLE)

1. A significantly greater proportion of patients in the voclosporin group achieved complete renal responses after 52 weeks compared to the placebo group. 2. The safety profile between the voclosporin group and placebo group were comparable with 21% of patients in both groups experiencing serious adverse events. Evidence Rating Level: 1...
1. In this retrospective cohort study, the authors observed that the greater decline in in-hospital maternal mortality was found for systemic lupus erythematosus (SLE) pregnancies compared to non-SLE pregnancies. 2. Despite reductions in in-hospital maternal mortality for SLE pregnancies, the rates still remain high and improvements are needed. Evidence Rating Level:...
1. In this retrospective cohort study, the authors observed that the greater decline in in-hospital maternal mortality was found for systemic lupus erythematosus (SLE) pregnancies compared to non-SLE pregnancies. 2. Despite reductions in in-hospital maternal mortality for SLE pregnancies, the rates still remain high and improvements are needed. Evidence Rating Level:...
1. For patients with Lupus nephritis end stage renal disease (LN ESRD), renal transplant reduced the risk of death by about 70%. 2. The risk reduction was driven primarily by decreased risk of death from cardiovascular disease and infection. Evidence Rating Level: 2 (Good) Study Rundown: Lupus nephritis (LN) is a common...