Tag: cardiovascular disease

1. Finerenone treatment lowered the risk of chronic kidney disease (CKD) progression in patients diagnosed with type 2 diabetes and advanced CKD. 2. Treatment with finerenone also lowered the risk of cardiovascular events in patients diagnosed with type 2 diabetes and advanced CKD. Evidence Rating Level: 1 (Excellent) Study Rundown: The leading...

1. Increased levels of circulating ACE2 were associated with greater risk of cardiovascular and non-cardiovascular death, heart failure, myocardial infarction, stroke, and diabetes. 2. Compared to other clinical risk factors such as diabetes, body-mass index, smoking status, non-HDL cholesterol, and systolic blood pressure, plasma ACE2 was the strongest predictor...

The Incidence, Risk Factors and In-Hospital Mortality of Acute Kidney Injury in Patients After Surgery for Acute Type A Aortic Dissection: A Single-Center Retrospective Analysis of 335 Patients 1. For patients undergoing surgical interventions for acute type A aortic dissections (AAAD), post-operative acute kidney injury was shown to increase patient...

1. An opportunistic screening protocol for atrial fibrillation was not found to improve diagnostic rates, compared to usual care. Evidence Rating Level: 1 (Excellent) Atrial fibrillation (AF) is a cardiac arrhythmia that increases in prevalence with age. AF can also lead to cardiovascular conditions such as stroke and heart failure. Although...

1. A 6% risk reduction for developing hypertension was associated with a 1-point improvement in Life’s Simple 7 score, a metric for cardiovascular health. Evidence Rating Level: 2 (Good) Hypertension is a condition that affects roughly half of the adult US population, and is a known risk factor for cardiovascular disease...

1. The standardized Ready to Reduce Risk (3R) program resulted in improvements to lifestyle among those taking medication for prevention of cardiovascular disease. 2. 3R did not improve medication adherence compared to the control group. Evidence Rating Level: 2 (Good) Nearly one-third of deaths across the globe are attributable to cardiovascular disease...

1. Gut Bacterial Species Shown to Lower Fecal and Serum Cholesterol Levels in Humans Evidence Rating Level: 2 (Good) High serum cholesterol levels have been linked to cardiovascular disease, the cause of 1 in 4 deaths in all industrialized countries. Reducing cholesterol transport in the intestine, as demonstrated by ezetimibe, a...

1. Depressive symptoms were associated with increased incident cardiovascular disease and all-cause mortality across multiple countries and communities at varying stages of economic development. 2. The strength of the association was highest in populations living in urban areas. Evidence Rating Level: 2 (Good) Depression has been shown to be associated with increased...

1. In this cohort of women, those who experienced migraines with aura were associated with an increased adjusted incidence rate for major cardiovascular diseases (CVD) compared to those with migraines without aura or no migraines. 2. After diabetes and smoking, migraines with aura were found to have the highest CVD...

1. Underlying cardiovascular disease was shown to be associated with increased risk of in-hospital death among coronavirus disease 2019 (Covid-19) hospitalized patients. 2. Angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) were not shown to be associated with in-hospital mortality among COVID-19 hospitalized patients. Evidence Rating Level: 2 (Good) Study Rundown: Recently, there is...