Tag: cardiovascular disease

1. Gut Bacterial Species Shown to Lower Fecal and Serum Cholesterol Levels in Humans Evidence Rating Level: 2 (Good) High serum cholesterol levels have been linked to cardiovascular disease, the cause of 1 in 4 deaths in all industrialized countries. Reducing cholesterol transport in the intestine, as demonstrated by ezetimibe, a...

1. Depressive symptoms were associated with increased incident cardiovascular disease and all-cause mortality across multiple countries and communities at varying stages of economic development. 2. The strength of the association was highest in populations living in urban areas. Evidence Rating Level: 2 (Good) Depression has been shown to be associated with increased...

1. In this cohort of women, those who experienced migraines with aura were associated with an increased adjusted incidence rate for major cardiovascular diseases (CVD) compared to those with migraines without aura or no migraines. 2. After diabetes and smoking, migraines with aura were found to have the highest CVD...

1. Underlying cardiovascular disease was shown to be associated with increased risk of in-hospital death among coronavirus disease 2019 (Covid-19) hospitalized patients. 2. Angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) were not shown to be associated with in-hospital mortality among COVID-19 hospitalized patients. Evidence Rating Level: 2 (Good) Study Rundown: Recently, there is...

1. Compared to healthy matched controls, individuals with multiple sclerosis demonstrated significantly increased risk of cerebrovascular disease, acute coronary syndrome, cardiovascular disease-related mortality, and all-cause mortality. Evidence Rating Level: 2 (Good) Multiple sclerosis (MS) is an autoimmune disease characterized by the demyelination of nerve fibers in the central nervous system, resulting in...

This article has since been retracted by NEJM on 6/11/2020. This 2MM article summary is left unchanged for historical context.   1. Underlying cardiovascular disease was shown to be associated with increased risk of in-hospital death among coronavirus disease 2019 (Covid-19) hospitalized patients. 2. Angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) were...

1. Exposure to higher levels of air pollutants was associated with increased dementia incidence, with the 5 years preceding onset being the most impactful. 2. The association between dementia and air pollutant exposure was amplified in patients with cardiovascular disease, specifically heart failure and ischemic heart disease. Evidence Rating: 2 (Good) With increasing...

Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial 1. Patients receiving landiolol were more likely to achieve target heart rates of 60-94 following sepsis-related tachyarrhythmia and had significantly reduced incidence of new onset arrhythmia Evidence Rating: 1...

1. Regular consumption of fish oil is likely associated with decreased all-cause and cardiovascular disease risk. 2. Consumption of fish oil was associated with decreased incidence of cardiovascular events with effects being most pronounced in patients with hypertension. Evidence Rating: 2 (Good) Lifestyle modification and dietary supplementation have long been recognized as...

Severe Lung Injury Associated With Use of e-Cigarette, or Vaping, Products - California, 2019 1. Study findings suggest that use of THC-containing products and vitamin E acetate to be associated with outbreak of use-associated lung injury in California Evidence Level: 3 (Average): Despite e-cigarette, or vaping usage increasing in popularity in North...