Tag: cardiovascular disease

1. Patients without standard modifiable cardiovascular risk factors (SMuRFs) had a significantly higher all-cause mortality at 30 days after first presentation of STEMI. 2. Patients without SMuRFs were significantly less likely to receive statins, ACEIs, ARBs, or beta-blockers at discharge.  Evidence Rating Level: 2 (Good) Study Rundown: Standard modifiable cardiovascular risk factors...
1. Combined use of intracoronary near-infrared spectroscopy (NIRS) and intravascular ultrasound were effective at detecting untreated intracoronary lesions at high risk of major adverse cardiac event (MACE). 2. Highly lipidic lesions and large plaque burden were found to be independent predictors of non-culprit lesion-related MACEs. Evidence Rating Level: 2 (Good) Study Rundown:...
1. A diet with a high glycemic index was associated with an increased risk of death and cardiovascular disease. 2. Among those without preexisting cardiovascular disease, a high glycemic load was not associated with increased death. Evidence Rating Level: 2 (Good) Study Rundown: Foods with a high glycemic index (GI) raise blood...
1. The American Heart Association’s cardiovascular health index has clinical utility with an understudied sub-Saharan African population. 2. The targets for preventing atherosclerosis in this population are smoking, obesity, hypertension, hyperglycemia, and physical activity. Evidence Rating Level: 3 (Average) The American Heart Association’s cardiovascular health index (CVHI) is known to be a...
1. Positive fecal immunochemical test (FIT) results were associated with increased incidences of ischemic stroke, myocardial infarction, and all-cause mortality. Evidence Rating Level: 2 (Good) While fecal immunochemical tests (FIT) is a commonly used and effective screening tool for colorectal cancer (CRC), their clinical use in detecting other diseases is poorly known....
1. There was no significant difference in periprocedural myonecrosis between ticagrelor and clopidogrel among patients undergoing high-risk elective PCI. 2. Ticagrelor treatment was associated with an increased rate of minor bleeding at 30 days post-operation. Evidence Rating Level: 1 (Excellent) Study Rundown: Percutaneous coronary intervention (PCI) provides a safe therapeutic option for...
 1. Febuxostat was non-inferior to allopurinol for primary cardiovascular endpoints including hospitalization for non-fatal myocardial infarction or biomarker-positive acute coronary syndrome, non-fatal stroke, or cardiovascular death during the treatment period. 2. Treatment with febuxostat was not associated with an increase in cardiovascular or all-cause mortality compared to allopurinol. Evidence Rating Level:...
 1. In patients aged ≥75 years, LDL cholesterol-lowering therapies reduced the risk for major vascular events, including cardiovascular death, myocardial infarction, stroke, and coronary revascularization. 2. In older patients (≥75 years), the benefits in risk reduction were similar when compared to younger patients (< 75 years), and when comparing statin...
1. Statin use for primary intervention of cardiovascular disease is around 23% lower in lesbian, gay, and bisexual individuals compared to the general population. 2. Rates for secondary intervention of cardiovascular disease were comparable between the two populations. Evidence Rating Level: 3 (Average) Cardiovascular disease (CVD) is the foremost cause of death...
1. Finerenone treatment lowered the risk of chronic kidney disease (CKD) progression in patients diagnosed with type 2 diabetes and advanced CKD. 2. Treatment with finerenone also lowered the risk of cardiovascular events in patients diagnosed with type 2 diabetes and advanced CKD. Evidence Rating Level: 1 (Excellent) Study Rundown: The leading...