Tag: cardiovascular disease

1. Risk of cardiovascular death, myocardial infarction, stroke, and revascularization was lower in the fixed-dose combination pill group compared to control. 2. Fixed-dose combination strategies with aspirin resulted in greater reductions in mortality compared to without aspirin. Evidence Rating Level: 1 (Excellent) Study Rundown: Cardiovascular disease is among the leading causes of...
1. Long term consumption of a nutritionally rich, plant-centered diet starting in young adulthood was associated with a reduced risk of cardiovascular disease. Evidence Rating Level: 1 (Excellent) The leading cause of death in the United States is heart disease and therefore, cardiovascular health is a topic that is continuously being...
1. The study found that young adults born small for gestational age had reduced exercise capacity, with reduced maximal workload, oxygen consumption, and minor differences in cardiac morphology compared to individuals born within standard reference weights. 2. Additional long-term studies employing larger sample sizes and older participants are needed to...
1. Time spent cycling was associated with lower all-cause and cardiovascular disease-specific mortality in this multicenter European cohort study of patients with diabetes, independent of other exercise. 2. Taking up cycling over a five-year period was associated with lower mortality rates compared with those who did not cycle at all. Evidence...
1. The use of coronary artery calcium scoring was associated with significant improvements in the reclassification and discrimination of incident atherosclerotic cardiovascular disease. 2. Coronary artery calcium scoring may be beneficial as an adjunct to risk-enhancing factor assessment when identifying individuals at intermediate risk of atherosclerotic cardiovascular disease who would...
1. Weight loss surgery was associated with significant improvement in both macrovascular and microvascular function across subgroups of sex, race, and metabolic syndrome in addition to effective weight loss. 2. Variation in vascular response to bariatric intervention across subgroups underscores heterogeneity in physiological responses to weight loss and potential activation...
1. In this cohort study, 91% of patients with preserved ejection fraction heart failure had evidence of epicardial coronary artery disease and/or coronary microvascular dysfunction. 2. Due to the high prevalence of these conditions, coronary artery disease and coronary microvascular dysfunction may be unrecognized and underdiagnosed in patients hospitalized with...
1. Retrospective analysis of hospital records showed decreased hospital admission rates for non-COVID-19 diseases in Denmark since the first lockdown. 2. Mortality rates were also shown to be higher for non-COVID-19 diseases, including respiratory diseases, cancer, pneumonia, and sepsis. Evidence Rating Level: 2 (Good) Study Rundown: The COVID-19 pandemic has put a...
1. Preventative aspirin was used uniformly by persons with diabetes across age groups, while in persons without diabetes it was used less in young seniors (60-69 and 70-79) and equally in those 80+, potentially outside of clinical recommendations. 2. Based on the results of this study and current guidelines, a...
1. Older patients with polypharmacy who discontinued statins had increased rates of admissions for heart failure, all-cause emergency hospital admissions, cardiovascular outcomes, and all-cause death versus those that did not. Evidence Rating Level: 2 (Good) Study Rundown: With advanced age, patients have multiple comorbidities and are commonly treated with multiple drugs,...