• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Radial artery access associated with reduced mortality in management of acute coronary syndrome

byJeffrey CampbellandSai Folmsbee
November 10, 2015
in Cardiology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. In this systematic review and meta-analysis, radial percutaneous access during invasive management of acute coronary syndrome was associated with decreased mortality, major adverse coronary events, and major bleeding when compared to femoral access.

2. However, radial artery access was associated with higher cross-over to femoral access.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Early invasive treatment of acute coronary syndrome (ACS; a group of diseases including heart attacks) frequently relies upon insertion of a catheter through blood vessels to relieve blockages in arteries supplying the heart. Typically, the catheter is inserted either through a major artery in the leg (i.e., the femoral artery) or arm (i.e., the radial artery) to access the heart’s blood supply. However, there is conflicting evidence about safety and efficacy of femoral vs. radial artery access. Therefore, this study analyzed data from four major trials that compared femoral vs. radial access in catheter-based management of ACS. Overall, compared to femoral access, radial access was associated with significantly decreased risk of death, major negative cardiac events, and major bleeding in the 30 days following the procedure. Notably, procedures using radial artery access took marginally longer than procedures using the femoral artery; procedures that began with radial access more frequently required conversion to femoral-based procedures than vice versa, although rates of conversion were low. Although the included studies required minimum levels of proficiency to complete the procedures, provider experience and expertise with femoral vs. radial access may have impacted results, which may impact the generalizability of this analysis to clinical care. Nevertheless, these results provide compelling evidence that radial access may be safer than femoral access for catheter-based treatment of ACS.

Click to read the study published today in the Annals of Internal Medicine

Relevant Reading: Bleeding, Blood Transfusion, and Increased Mortality After Percutaneous Coronary Intervention: Implications for Contemporary Practice

RELATED REPORTS

Catheter-guided aortic valve replacement and angioplasty has favorable outcomes compared to surgical intervention

Optical coherence tomography-guided angioplasty reduces adverse events compared to angiography guidance

#VisualAbstract: FFR-Guided Complete Percutaneous Coronary Intervention Is Non-Superior to Culprit-Only Percutaneous Coronary Intervention

In-Depth [systematic review and meta-analysis]: This systematic review and meta-analysis pooled data from 17 133 patients enrolled in four large, high-quality, randomized clinical trials evaluating radial vs. femoral access for cardiac catheterization during ACS. Patients were followed for 30 days post-procedure. Overall, radial access was associated with decreased risk of all-cause mortality (relative risk 0.73, 95%CI 0.59 – 0.90, I2 0%), major adverse cardiac events (RR 0.86, 95%CI 0.75 – 0.98, I2 11%), access-site bleeding (RR 0.36, 95%CI 0.28 – 0.47, I2 0%), and major bleeding (RR 0.57, 95% 0.37 – 0.88, I2 52%). There was a 6.3% rate of crossover from radial to femoral access, compared to a 1.7% of crossover from femoral to radial access, although there was a high degree of heterogeneity between studies for this outcome (I2 88%). Notably, of the four trials included, only two included patients with non-ST elevation myocardial infarcts (NSTEMI).

Image: PD

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: acute coronary syndromespercutaneous coronary intervention
Previous Post

2 Minute Medicine Rewind November 2 – November 8, 2015

Next Post

Long-term safety of silicone gel breast implants is unclear

RelatedReports

Drug-coated balloons are noninferior to drug-eluting stents for treatment of small vessel coronary artery disease
Cardiology

Catheter-guided aortic valve replacement and angioplasty has favorable outcomes compared to surgical intervention

February 11, 2025
Drug-coated balloons are noninferior to drug-eluting stents for treatment of small vessel coronary artery disease
Cardiology

Optical coherence tomography-guided angioplasty reduces adverse events compared to angiography guidance

October 1, 2024
#VisualAbstract: FFR-Guided Complete Percutaneous Coronary Intervention Is Non-Superior to Culprit-Only Percutaneous Coronary Intervention
StudyGraphics

#VisualAbstract: FFR-Guided Complete Percutaneous Coronary Intervention Is Non-Superior to Culprit-Only Percutaneous Coronary Intervention

April 11, 2024
PCI not superior to medical therapy alone in stable coronary disease: The COURAGE study
Cardiology

Percutaneous coronary intervention associated with decreased stable angina symptoms

January 5, 2024
Next Post
Long-term safety of silicone gel breast implants is unclear

Long-term safety of silicone gel breast implants is unclear

Preeclampsia linked to autism and developmental delay

Intensive systolic blood pressure reduction below 140 mmHg reduces risk of major cardiovascular events

MRI helps predict risk of local recurrence in upper rectal cancers

Clinically undetected myocardial scars detected by cardiac MRI

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Sodium-glucose cotransporter 2 inhibitors may decrease risk of serious liver events in patients with cirrhosis
  • #VisualAbstract: Lactated Ringer’s Solution Does Not Improve Outcomes Relative to Normal Saline
  • 2MM: AI Roundup – FDA’s AI Push, Trial Speedups with Real-World Data, Smart Surgical Monitors, and Regulatory Overhaul Begins [July 2nd, 2025]
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.