• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Endocrinology

Roux-en-Y gastric bypass may slow progression of diabetic retinopathy

byRehan SaiyedandChaz Carrier
November 28, 2014
in Endocrinology, Ophthalmology, Surgery
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. In diabetic retinopathy patients undergoing Roux-en-Y gastric bypass, there was no significant progression of diabetic retinopathy scores after 2 years of follow-up.

2. A significant worsening of diabetic retinopathy scores was noted in control subjects who did not undergo gastric surgery.

Evidence Rating Level: 3 (Average)

Study Rundown: Roux-en-Y bypass has been linked to sustained weight loss in 90% of patients, with concomitant improvement of obesity-associated complications, including type II diabetes mellitus. While the efficacy of bariatric surgery for diabetic patients has been established, little is known regarding the effect of the surgery and concomitant weight loss on the progression of diabetic retinopathy (DR). This study found no significant change in diabetic retinopathy grading scores in patients 2 years after Roux-en-Y gastric surgery. This was in contrast with a matched group of DR patients managed with medical therapy, who experienced significant deterioration of their DR over the same period. These results illustrate the potential efficacy of Roux-en-Y surgery in limiting the progression of DR. However, this study suffers from a number of methodological drawbacks including significant baseline differences in the treatment and control groups. The control group tended to be more male, older, of a lower BMI, and, most notably, farther along in their diabetic course, with increased time with diabetes, incidence of insulin dependence, and baseline DR grading scores. Such deficiencies, coupled with the small simple size, limit the generalizability of these results.

Click to read the study in Obesity Surgery

Relevant Reading: Lifestyle, Diabetes, and Cardiovascular Risk Factors 10 Years after Bariatric Surgery

In-Depth [case-control study]: Data was collected via a National Health Service (NHS) Database from 21 cases with type II diabetes and grade 1 or higher DR who underwent a Roux-en-Y gastric bypass procedure and had relevant retinal images 2 years post-operatively. Twenty-four individuals with type II diabetes and retinopathy of grade 1 or higher served as the control group. Retinal scans or ophthalmic documentation were utilized to assess DR by a blinded ophthalmologist and graded at baseline and 2 years later. In the treatment group, DR grading scores increased from 1.29 at baseline to 1.52 at 2 years post-op; however this change was not significant (p = 0.14). A significant increase in DR from 2.21 at baseline to 2.58 at two year follow-up was noted in the control group (p = 0.03). There was no significant difference in the change of DR scores between the treatment and control groups (p = 0.13).

RELATED REPORTS

Faricimab may improve visual acuity in patients with diabetic macular edema

Supplementation of tirzepatide for type 2 diabetics on basal insulin improved glycemic control compared to placebo

Tirzepatide is superior to insulin glargine for management of type 2 diabetes and elevated cardiovascular risk

More from this author: Vitamin deficiency may persist after Omega-loop gastric bypass, Age-related confounders may contribute to heart transplant mortality, CA19-9 kinetics may predict pancreatic cancer resectability

Image: PD

©2014 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. No article should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2 Minute Medicine, Inc.

 

Tags: bariatric surgerydiabetic retinopathyType 2 Diabetes Mellitus
Previous Post

Global surveillance of cancer trends reveals wide variances in survival rate [CONCORD-2 study]

Next Post

Multiple colposcopy biopsies may improve cervical cancer precursor detection

RelatedReports

Blindness and visual impairment decreasing worldwide
Chronic Disease

Faricimab may improve visual acuity in patients with diabetic macular edema

March 8, 2022
Insulin costs rose exponentially, regardless of formulation or patent
Cardiology

Supplementation of tirzepatide for type 2 diabetics on basal insulin improved glycemic control compared to placebo

February 9, 2022
Cardiology

Tirzepatide is superior to insulin glargine for management of type 2 diabetes and elevated cardiovascular risk

January 11, 2022
Food environment associated with gestational diabetes
Chronic Disease

Prevalence of diabetes mellitus in China, 2013-2018

December 29, 2021
Next Post
Multiple colposcopy biopsies may improve cervical cancer precursor detection

Multiple colposcopy biopsies may improve cervical cancer precursor detection

Patient Basics: Yaws

Dual-energy CT may improve detection of acute small bowel ischemia

Dual-energy CT may improve detection of acute small bowel ischemia

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Stereotactic body radiotherapy as a state of the art treatment option in inoperable non-small cell lung cancer [Classics Series]
  • Health system-based care associated with better treatment use and high rates of tobacco abstinence at 3 months post-discharge in hospitalized smokers
  • APOEε4 genotype may increase risk of chronic traumatic encephalopathy following repetitive head impact
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.