• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Severe endometriosis associated with poor IVF outcomes

bys25qthea
July 7, 2013
in Chronic Disease, Obstetrics
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

Image: PD

1. Women with Stage III/IV endometriosis undergoing in vitro fertilization (IVF) had lower rates of implantation and clinical pregnancy. 

2. Women with Stage I/II endometriosis had lower fertilization rates. 

Evidence Rating Level: 2 (Good) 

Study Rundown: This study found that women with endometriosis experienced a higher incidence of adverse IVF outcomes. Major findings include the observed association between advanced endometriosis (Stage III/IV) and lower rates of implantation and clinical pregnancy. Past studies have suggested that the degree of endometriosis may affect IVF outcomes in a dose-dependent fashion, and the findings of the present work support this. This meta-analysis adds new information to the literature base by including data through 2012 and excluding women who received medical or surgical interventions for endometriosis prior to IVF to achieve a more parsimonious study design.

Strengths of this meta-analysis include a large pooled sample size and evaluation of the methodological quality of included studies. Limitations include heterogeneity across studies, such as the timing of reported IVF outcomes and methods used to diagnose endometriosis. Future studies might compare women who received interventions for endometriosis prior to IVF with those who did not to evaluate whether treatment of endometriosis improves IVF outcomes. 

Click to read the study in the British Journal of Obstetrics & Gynaecology

RELATED REPORTS

Mediterranean diet superior to low-fat diet in secondary prevention of cardiovascular events

Virtual yoga and meditation intervention may be associated with increased health-related quality of life

Endometriosis associated with early natural menopause

Relevant Reading: UpToDate: Pathogenesis and treatment of infertility in women with endometriosis

In-Depth [meta-analysis]: This systematic review evaluated the relationship between endometriosis and IVF outcomes. Data was abstracted from 27 observational studies examining IVF outcomes for women with endometriosis (n=1490) and women without endometriosis (n=7494) from 1985 through 2012. Included studies were evaluated for methodological quality using the Newcastle-Ottawa Scale. Outcomes evaluated include fertilization, implantation, clinical pregnancy and live birth rates.

Compared to women undergoing IVF for other indications, women with endometriosis demonstrated poorer IVF outcomes. Women with Stage I/II endometriosis had lower fertilization rates (RR 0.93, CI 0.87-0.99). Women with Stage III/IV endometriosis had lower implantation rates (RR 0.79, CI 0.67-0.93) and clinical pregnancy rates (RR 0.79, CI 0.69-0.91). While it did not reach statistical significance, women with Stage III/IV endometriosis also had a lower live birth rate (RR 0.86, CI 0.68-1.08).

By Denise Pong, MPH and Leah Hawkins, MD, MPH

More from this author: New guidelines for intrapartum management of patients with mental disorders, Oral glucose tolerance test preferred for pre-diabetes screening in PCOS, Vaginal misoprostol improves ease of IUD insertion

© 2013 2minutemedicine.com. All rights reserved. No works may be reproduced without written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT. Content is produced in accordance with fair use copyrights solely and strictly for the purpose of teaching, news and criticism. No benefit, monetary or otherwise, is realized by any participants or the owner of this domain. 

Tags: endometriosishealthin vitro fertilizationIVF
Previous Post

The CHARM-Alternative trial: Angiotensin-receptor blockers in heart failure [Classics Series]

Next Post

Low incidence and high clearance of oral HPV infections in men

RelatedReports

FDA-approved weight loss medications associated with weight loss at one year
Cardiology

Mediterranean diet superior to low-fat diet in secondary prevention of cardiovascular events

May 25, 2022
Exercise intervention linked to reduced functional decline among elderly patients admitted to the hospital
Wellness

Virtual yoga and meditation intervention may be associated with increased health-related quality of life

May 20, 2022
Early language exposure is predictive of language skills and IQ in school-age children
Chronic Disease

Endometriosis associated with early natural menopause

January 24, 2022
Vegetarian diet may lower incidence of colorectal cancer
Wellness

Monthly subsidy increased purchase of fresh fruits and vegetables in Supplemental Nutrition Assistance Program beneficiaries

October 18, 2021
Next Post
Reduced HPV vaccine doses may be adequate

Low incidence and high clearance of oral HPV infections in men

Half of parents aware of CT radiation cancer risk

Half of parents aware of CT radiation cancer risk

Prenatal alcohol-induced developmental delay is dose and time dependent

Prenatal alcohol-induced developmental delay is dose and time dependent

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Vitamin and mineral supplementation associated with minimal to no benefit in the primary preventing of cardiovascular disease and cancer – US Preventative Services Task Force
  • RSVpreF vaccine prevents symptomatic respiratory syncytial virus infection
  • Incidence of Kawasaki disease found to be lower during the COVID-19 pandemic in the United States
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.