Tag: health

Image: PD 1. Women with PCOS were more likely to have a preterm delivery. 2. Among women with PCOS, those who exhibited hyperandrogenism were more likely to experience preeclampsia and preterm delivery. Evidence Rating Level: 2 (Good) Study Rundown: This study found that polycystic ovarian syndrome (PCOS) was associated with adverse...
Image: PD  1.  Patients diagnosed with stage III or IV melanoma are at risk for the development of further primary melanomas, particularly if they have a history of multiple primary melanomas prior to their diagnosis.  Evidence rating level: 2 (Good) Study Rundown: In recent year, B-raf inhibitors such as Vemurafenib have been...
Image: PD 1. Tranexamic acid significantly reduces all-cause mortality in trauma patients with significant hemorrhage. 2. There were no significant differences between the tranexamic acid and placebo groups with regards to the incidence of vascular occlusive events or the need for transfusion or surgery. Original Date of Publication: July 3, 2010 Study Rundown: While...
Image: PD 1. Patients with high suppressor of tumorigenicity 2 (ST2) levels at the initiation of graft-vs-host-disease (GVHD) therapy were more likely to have treatment-resistant GVHD and to die within 6 months of therapy initiation.  2. Plasma ST2 values measured at day 14 after transplantation is a better predictor of death...
Image: PD  1. 5.6% of adolescents in this study used smokeless tobacco with 72.1% of smokeless tobacco users concurrently smoking tobacco.  2. Perception of harm of all tobacco products was protective and was significantly correlated with reduced use of smokeless tobacco.  Evidence Rating Level: 2 (Good)  Study Rundown: Tobacco use among adolescents is...
Image: PD  1. Among patients with no history of strokes or cardiac events, abnormal left ventricular global longitudinal strain (GLS) correlated with silent cerebral infarcts (SBI) and white matter hyperintensities (WMH). 2. Differences in left ventricular ejection fraction (LVEF) were not differentiators for these subtle signs of cerebrovascular disease. Evidence Rating Level:...
Image: CC/Osaro 1. Treatment with lenalidomide and dexamethasone significantly delayed disease progression in patients with smoldering multiple myeloma who were at high risk for progression. 2. Treatment with lenalidomide and dexamethasone improved survival in such patients. 3. The treatment was associated with more adverse events than observation (current standard). Evidence Rating Level: 1...
Image: PD  1. An estimated 111,914 children presented to emergency departments in the United States for non-fatal, food-related choking episodes from 2001-2009.  2. Children ages 0-4 years experienced the highest rate of choking episodes during the study period.  Evidence Rating Level: 2 (Good) Study Rundown: Choking is one of the leading causes of...
Image: PD 1. African American women were more likely to present with vulvar cancer at a younger age compared to white women. 2. Among women ≥ 60 years of age, African Americans had lower vulvar cancer related mortality.  Evidence Rating Level: 2 (Good) Study Rundown: This study explored the epidemiology of vulvar...
Image: PD  1) Hepatitis C virus (HCV) liver transplant (LT) recipients receiving perioperative transfusions have increased fibrosis and decreased 1- and 5-year survival when compared to their non-transfused counterparts.  2) Negative impact of transfusion may be due to early immune modulation leading to suppression of HCV-specific IFN-gamma and activation of IL-17.  Evidence...