Tag: health

Image: PD 1. Use of semagacestat was associated with dose-relevant clinical worsening.  2. There were also renal and immunologic effects with semagacestat use, many of which persisted long after termination of treatment. Evidence Rating Level: 1 (Excellent)      Study Rundown: In this phase-3 clinical trial, semagacestat did not improve cognitive or functional...
Image: PD  1. No mortality benefit was observed among white Norwegian adults randomly selected for echocardiographic screening for structural heart disease.  2. No difference was observed in sudden death, death from cardiovascular disease, myocardial infarction or stroke.  Evidence Rating Level: 1 (Excellent)  Study Rundown: Echocardiography is a non-invasive, low-risk procedure with high sensitivity...
Image: PD 1. During 1990-2011, TV-related injuries occurred in 2.43 per 10,000 children. 2. Injuries related to falling TVs increased by 95% over the study period. Evidence Rating Level: 2 (Good)            Study Rundown: Falling televisions are significant sources of morbidity within the pediatric population. Greater than 99% of...
Image: PD  1. One year of adjuvant Herceptin (trastuzumab) has similar efficacy as a two-year regimen.  2.  One-year regimen was associated with a lower incidence of adverse events.  Evidence Rating Level: 1 (Excellent)        Study Rundown: This large scale, randomized controlled trial found that two years of Herceptin treatment has an...
Image: PD 1. Patients undergoing pancreatectomy for malignancy may benefit from islet autotransplantation (IAT) used to prevent brittle diabetes.  2. Post-pancreatecmy patients with malignant disease who underwent IAT had similar disease-free and overall survival to similar patients who did not receive an autotransplant.  Evidence Rating Level: 2 (Good)        ...
Image: PD  1. Individuals at high risk of lung cancer stand to benefit from screening with low-dose CT, whereas those at low risk of lung cancer do not.  Evidence Rating Level: 1 (Excellent)      Study Rundown: The National Lung Screening Trial (NLST) identified individuals at high risk of lung cancer by...
Image: PD 1. From 2000 to 2009, neonatal intensive care units (NICUs) increased use of antenatal steroids, cesarean delivery, surfactant in the delivery room, and less-invasive respiratory support for very low birth weight infants (VLBW).  2. Decreases in steroid use for chronic lung disease, delayed surfactant use, and endotracheal tube ventilation...
Image: PD 1. A prediction algorithm was effective in helping researchers identify infants at-risk for becoming overweight at three years of age.  2. Observed risk values significantly correlated with algorithm calculated risk scores—suggesting strength within the model.  Evidence Rating Level: 2 (Good)  Study Rundown: Research shows that obesity has a measurable impact on...
Image: PD 1. An enhanced recovery protocol was associated with shortened hospital stays and reduced costs among patients undergoing major gynecologic surgeries (cytoreduction, surgical staging, or pelvic organ prolapse surgery).  2. Enhanced recovery protocols were associated with decreased use of patient-controlled anesthesia.  Evidence Rating Level: 2 (Good)  Study Rundown: This study found that...
Image: PD 1. In a retrospective study, preterm delivery was an independent risk factor for future maternal cardiovascular-related hospitalizations.  2. The risk of maternal cardiovascular morbidity increased in a dose-dependent fashion with the number of preterm births.  Evidence Rating Level: 2 (Good)  Study Rundown: This population-based, retrospective cohort study identified a dose-dependent increase...