Tag: acute coronary syndrome

1. Patients without standard modifiable cardiovascular risk factors (SMuRFs) had a significantly higher all-cause mortality at 30 days after first presentation of STEMI. 2. Patients without SMuRFs were significantly less likely to receive statins, ACEIs, ARBs, or beta-blockers at discharge.  Evidence Rating Level: 2 (Good) Study Rundown: Standard modifiable cardiovascular risk factors...
1. Combined use of intracoronary near-infrared spectroscopy (NIRS) and intravascular ultrasound were effective at detecting untreated intracoronary lesions at high risk of major adverse cardiac event (MACE). 2. Highly lipidic lesions and large plaque burden were found to be independent predictors of non-culprit lesion-related MACEs. Evidence Rating Level: 2 (Good) Study Rundown:...
1. The PRAISE score showed accurate discriminative capabilities for the prediction of all-cause death, acute myocardial infarction, and major bleeding after an acute coronary syndrome. 2. Compared with low risk stratification, a high-risk PRAISE score was associated with a 58.8-times increase in death, 27.7-times increase in myocardial infarction, and a...
 1. In patients aged ≥75 years, LDL cholesterol-lowering therapies reduced the risk for major vascular events, including cardiovascular death, myocardial infarction, stroke, and coronary revascularization. 2. In older patients (≥75 years), the benefits in risk reduction were similar when compared to younger patients (< 75 years), and when comparing statin...
1. Patients status-post placement of drug-eluting stents (DES) for acute coronary syndrome received three months of Ticagrelor and Aspirin dual-antiplatelet therapy (DAPT), followed by nine months of DAPT or Ticagrelor monotherapy. 2. At one year, patients who received Ticagrelor alone experienced significantly fewer adverse major bleeding events. There was no...
Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease 2019 (COVID-19) 1. No association was found between angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker use and test-positivity for COVID-19. Evidence Rating Level: 2 (Good) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the...
The following study summary is an excerpt from the book 2 Minute Medicine’s The Classics in Radiology: Summaries of Clinically Relevant & Recent Landmark Studies, 1e (The Classics Series). 1. In patients presenting to the emergency department with acute chest pain, evaluation with computed tomographic coronary angiography (CTCA) led to significantly...
The following study summary is an excerpt from the book 2 Minute Medicine’s The Classics in Radiology: Summaries of Clinically Relevant & Recent Landmark Studies, 1e (The Classics Series). 1. In patients presenting with chest pain and a low to intermediate risk of acute coronary syndrome (ACS), computed tomographic coronary angiography...
1. On average, in this cross-sectional study, physician visual assessment overestimated coronary stenosis severity as compared to quantitative coronary angiography. 2. There was wide variation across hospitals and physicians when comparing severity of coronary stenosis. Evidence Rating Level: 3 (Average) Study Rundown: The presence and severity of coronary stenosis is determined by...
A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults A vaccine against Neisseria meningitidis serotype B is needed, as current polysaccharide-based vaccines do not cover this serotype. A bivalent vaccine, MenB-FHbp, containing factor H-binding protein variants has been licensed in the US, however, large assessment of its coverage and...