Tag: ALS

1. Sodium phenylbutyrate-taurursodiol slowed the functional decline in patients with amyotrophic lateral sclerosis. 2. The mean rate of change for slow vital capacity and plasma phosphorylated axonal neurofilament H subunit were not significantly different between the treatment and control groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Amyotrophic lateral sclerosis (ALS) causes...
1. A 100mg treatment of tofersen was shown to decrease cerebrospinal fluid (CSF) superoxide dismutase 1 (SOD1) concentration in adults with amyotrophic lateral sclerosis (ALS) due to SOD1 mutations. 2. Lumbar puncture-related adverse events were shown to be present in most participants. Evidence Rating Level: 1 (Excellent) Study Rundown: Amyotrophic lateral sclerosis,...
Originally published by Harvard Health. What Is It? Amyotrophic lateral sclerosis (ALS) causes a slow degeneration of nerve cells that control muscle movements. As a result, people with ALS gradually lose the ability to control their muscles. Fortunately, their capacity to think and remember things usually is not affected. ALS is...