Tag: alzheimer

1. This prospective cohort study showed that mentally stimulating activities (computer use, craft activities, social activities and playing games) in late-age (>70 years old) were associated with decreased risk of incident mild cognitive impairment (MCI). 2. When stratified by apolipoprotein E ε4 (APOE ε4) carrier status, those at lowest risk...
1. Regardless of treatment intervention, all patients had progressive functional decline. 2. No statistically significant difference was observed in Activity of Daily Living Scale (ADL) for patients receiving occupational therapy versus no occupational therapy after 1 year. Evidence Rating Level: 1 (Excellent) Study Rundown: Alzheimer disease leads to progressive functional decline and...
1. Based on a retrospective cohort study of Alzheimer’s disease patients, history of cardiovascular risk factors was not associated with increased risk of late-onset Alzheimer’s disease, but history of stroke was strongly associated with this diagnosis. 2. History of hypertension was inversely associated with risk of late-onset Alzheimer’s disease. Evidence Rating...
Originally published by Harvard Health. What Is It? Alzheimer's disease (AD) is a loss of brain functions that worsens over time. It is a form of dementia. Alzheimer’s disease damages the brain's intellectual functions. Short term memory often is affected early. Gradually other intellectual functions deteriorate. Judgment becomes impaired. Most people with...
Image: PD. PET scans of healthy vs. diseased brains 1. ABCA7 variants are associated with an increased risk of Alzheimer Disease in African Americans, more so than in non-Hispanic whites. 2. ABCA7 encodes an ATP binding cassette transporter, which interacts with apolipoproteins and thus affects lipid metabolism. Study Rundown: In this retrospective...