Anti-tau antibody Semorinemab not shown to slow clinical progression of Alzheimer’s disease
1. In this randomized controlled trial, among 457 participants with prodromal to mild Alzheimer’s disease, semorinemab was not shown to ...
Tag: alzheimer
Alzheimer disease in individuals with Down syndrome has similar variability in age of onset and mortality rate as autosomal dominant forms
1. This systematic review and meta-analysis demonstrated that the onset of Alzheimer disease in people with Down syndrome is as ...
Early onset Lewy Body Dementia is more clinically distinct from Alzheimer Dementia than late onset Lewy Body Dementia
1. Select features distinguish early-onset Lewy Body Dementia from early-onset Alzheimer dementia, including: hallucinations, slowness, apathy and motor deterioration. 2. ...
Familial natural short sleep mutations may reduce Alzheimer’s Disease pathology in mice [PreClinical]
1. Certain sleep phenotypes, such as those with the familial natural short sleepers (FNSS) mutation, anecdotally do not exhibit the ...
Wellness Check: Sleep
2 Minute Medicine is pleased to announce that we are launching Wellness Check, a new series dedicated to exploring new ...
Mirtazapine not effective in treating agitation in patients with dementia
1. Compared to placebo, mirtazapine did not significantly reduce agitation in patients with dementia. 2. There was no significant difference ...
Methylphenidate associated with short-term reduction in symptoms of apathy in patients with Alzheimer disease
1. Methylphenidate provides a treatment approach with modest but potentially clinically significant benefit for apathy symptoms in patients with Alzheimer ...
Non-drug interventions highly efficacious at reducing depressive symptoms in people with dementia
1. Systematic review found that social prescribing was associated with a reduction in depressive symptoms in patients with dementia without ...
Late-life mentally stimulating activities may decrease risk of mild cognitive impairment
1. This prospective cohort study showed that mentally stimulating activities (computer use, craft activities, social activities and playing games) in ...
Long-term collaborative care and occupational therapy did not slow functional decline in patients with dementia
1. Regardless of treatment intervention, all patients had progressive functional decline. 2. No statistically significant difference was observed in Activity ...