Tag: aortic valve replacement

1. Patients with asymptomatic severe aortic stenosis receiving early valve replacement had a lower incidence of operative mortality or death due to cardiovascular causes compared to patients receiving conservative care Evidence Level: 1 (Excellent) Aortic stenosis is the most common valvular disease with surgical indications in developed countries, with aortic-valve replacement being...

1. This randomized clinical trial showed that cerebral embolic protection devices did not significantly reduce the risk of CNS infarction among patients with calcific aortic stenosis undergoing SAVR. 2. However, fewer patients experienced delirium at postoperative day 7 in the cerebral embolic protection devices group compared to control. Evidence Rating Level:...

1. Among patients at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) was shown to be noninferior to surgery with respect to the primary end point of death or disabling stroke at 24 months. 2. Patients who underwent surgery had higher rates of acute kidney injury, atrial fibrillation, and transfusion,...

1. Administration of fibrinogen concentrate in patients undergoing high-risk cardiac surgery did not significantly reduce intraoperative blood loss. Evidence Rating Level: 1 (Excellent) Study Rundown: Intraoperative bleeding remains one of the most common complications in cardiac surgery. Plasma fibrinogen deficiency often develops when the ongoing blood loss is substituted with red...

1. Among all patients undergoing transcatheter aortic valve replacement, an increased risk of infective endocarditis was found in males, younger age groups, those with a history of diabetes mellitus, and those with aortic regurgitation. 2. Those patients who developed infective endocarditis had a significantly elevated rate of in-hospital mortality and...

1. The number and volume of new brain lesions was lower in patients with an implanted cerebral protection device following transcatheter aortic valve implantation 2. There was no difference in the rate of complications in patients with the cerebral protection device compared to controls.   Evidence Rating Level: 1 (Excellent) Study Rundown:...

1. For intermediate-risk surgical candidates with aortic stenosis, transcatheter aortic-valve replacement (TAVR) was non-inferior to surgical aortic-valve replacement based on all-cause death and disabling stroke at 2 years, as well as 30-day clinical endpoints. 2. TAVR had better aortic valve area and gradient compared to surgery based on echocardiographic...

1. For patients aged 50-69 years, there was no significant difference in long-term survival when comparing bioprosthetic and mechanical aortic valve replacement. 2. Mechanical valve replacement was associated with a lower rate of reoperation and higher rate of major bleeding compared to bioprosthetic valve replacement. Evidence Rating Level: 2 (Good) Study Rundown:...

1. When compared with bioprosthetic aortic valve replacements (AVR), mechanical AVRs were associated with increased mortality on the date of surgery and in early days after the operation amongst older Americans. 2. This difference in mortality was not present between the two forms of AVR 30 days after the...

Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Comparison of Balloon-Expandable vs Self-expandable Valves in Patients Undergoing Transcatheter Aortic Valve Replacement The CHOICE Randomized Clinical Trial Inoperable patients with severe aortic stenosis can now elect to undergo transcatheter aortic...