Tag: atopic dermatitis

1. In this study, nemolizumab with topical agents and oral antihistamines when compared to topical agents and oral antihistamines alone reduced pruritis in atopic dermatitis patients 2. Among patients in the nemolizumab group, eczema area, quality of life and insomnia improved when compared with placebo. Evidence Rating Level: 1 (Excellent) Study Rundown:...
1. Commonly prescribed antibiotics in infancy are associated with later diagnosis of allergic disease in childhood Evidence Rating Level: 2 (Good) The use of antibiotics negatively impacts the human microbiome, decreasing bacterial diversity. These kinds of changes to the microbiome have been previously found to be associated with allergic disease. In...
1. In treatment-resistant childhood atopic dermatitis, omalizumab significantly reduced the severity of dermatitis and improved quality of life compared to placebo.  Evidence Rating Level: 1 (Excellent) Anti-IgE medications such as omalizumab are well-tolerated in patients with severe asthma and atopy; however, no large randomized trials have examined its efficacy in children experiencing...
1. In treatment-resistant childhood atopic dermatitis, omalizumab significantly reduced the severity of dermatitis and improved quality of life compared to placebo.  Evidence Rating Level: 1 (Excellent) Anti-IgE medications such as omalizumab are well-tolerated in patients with severe asthma and atopy; however, no large randomized trials have examined its efficacy in children...
Association of Anticoagulant Therapy With Risk of Fracture Among Patients With Atrial Fibrillation 1. Direct oral anticoagulants, specifically apixaban, were associated with lower risk of fracture in patients with atrial fibrillation compared to warfarin. Evidence Rating Level: 2 (Good) Warfarin is commonly used to prevent cardioembolic events in individuals with atrial fibrillation...
Atopic dermatitis, a common disorder in the pediatric population, is associated with pruritus that is often worse at night and, thus, can interfere with sleep. This longitudinal cohort study aimed to assess whether active atopic dermatitis impacts sleep duration and quality, and to examine the association between severity of...
Veverimer Versus Placebo in Patients with Metabolic Acidosis Associated with Chronic Kidney Disease: a Multicenter, Randomized, Double-Blind, Controlled, Phase 3 Trial Chronic metabolic acidosis is often seen in patients with chronic kidney disease (CKD), and results from an inability to excrete metabolically produced acid. This, in turn, is associated with...