Tag: bariatric surgery

1. In patients with morbid obesity, intermittent intra-abdominal vagal nerve blockade did not induce significant body weight loss (>20%) when compared to a placebo device. 2. While the safety profile of the device itself was low, adverse events associated with abdominal surgery and anesthesia persist. Evidence Rating Level: 1...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week.  CPAP, Weight Loss, or Both for Obstructive Sleep Apnea Obstructive sleep apnea (OSA) and obesity are both independently associated with insulin resistance, dyslipidemia, hypertension, and inflammation. They are also strongly associated to...
1. Weight loss surgery was associated with a higher rate of sustained diabetes remission than standard care with lifestyle modification and pharmacotherapy.  2. Weight loss surgery was also associated with lower rates of microvascular and macrovascular complications of diabetes.  Evidence Rating Level: 2 (Good) Study Rundown: Obesity is an important risk factor...
Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing A Randomized Trial of Genotype-Guided Dosing of Warfarin Warfarin metabolism has been previously shown to be partially genetically determined with polymorphisms CYP2C9*2,...
Image: PD  1. Obese women who underwent bariatric surgery reported significant improvement in sexual functioning at two years.  2. These women also had increased reproductive hormone levels and improved psychosocial status.  Evidence Rating Level: 1 (Excellent)  Study Rundown: While bariatric surgery is performed with the goal of improving medical outcomes, several studies have...
Image: PD 1. Relative to the time before surgery, opioid use was increased by 18% over the 3 years following bariatric surgery. 2. Of the study sample, 77% of chronic opioid users continued chronic use after bariatric surgery. Evidence Rating Level: 2 (Good) Study Rundown: Chronic pain is a known co-morbid condition of...
Image: PD 1. 50% of patients with type II diabetes who underwent bariatric surgery achieved complete or partial remission after five years of follow-up. This was associated with a shorter duration of pre-operative diabetes and a higher degree of lasting weight loss.  2. Patients whose diabetes recurred demonstrated improved glycemic, blood...
Image: PD 1. In severely obese individuals, perivascular adipose tissue (PVAT) showed dysfunction prior to bariatric surgery and showed restored function when resampled six months postoperatively.   2. Improvements to PVAT function and resulting small artery tone occurred while patients remained severely obese.   Evidence Rating Level: 2 (Good)   Study Rundown: Perivascular adipose tissue (PVAT)...
Image: PD 1.     Weight loss and glycemic control are improved in the short term to a greater extent in nonmorbidly obese diabetic patients who have undergone bariatric surgery relative to nonsurgical intervention. 2.     Gastric bypass was more effective than gastric banding for weight loss and glycemic control. 3.     Since the literature does...
Image: PD 1. 1 month complication rates in increasing order: laparoscopic-adjustable gastric banding (LAGB), sleeve gastrectomies (SG), laparoscopic gastric bypass (RYGB). 2. Weight loss at one year as percentage of body weigt: 34% for LAGB, 60% for SG, and 69% for RYGB.  3. SG is nearly as effective at as RYGB when...