Tag: Breast Cancer

Hyperthyroidism is associated with breast cancer risk and mammographic and genetic risk predictors 1. Hyperthyroidism was associated with a higher rate of breast cancer among women. 2. Risk was particularly elevated for those with toxic nodular goiter. Evidence Rating Level: 2 (Good) Breast cancer is the most common cancer among women across the...

1. Targeted intraoperative radiotherapy for breast cancer has comparable long-term cancer-related outcomes as whole breast post-operative radiotherapy, and lower mortality from other causes. Evidence Rating Level: 1 (Excellent) Breast cancer is one of the most common cancers worldwide, with 2 million diagnoses and 626 000 deaths in 2018 alone. The treatment...

Hyperthyroidism is associated with breast cancer risk and mammographic and genetic risk predictors 1. Hyperthyroidism was associated with a higher rate of breast cancer among women. 2. Risk was particularly elevated for those with toxic nodular goiter. Evidence Rating Level: 2 (Good) Breast cancer is the most common cancer among women across the...

1. Targeted intraoperative radiotherapy for breast cancer has comparable long-term cancer-related outcomes as whole breast post-operative radiotherapy, and lower mortality from other causes. Evidence Rating Level: 1 (Excellent) Breast cancer is one of the most common cancers worldwide, with 2 million diagnoses and 626 000 deaths in 2018 alone. The treatment...

Air pollution and family related determinants of asthma onset and persistent wheezing in children: nationwide case-control study 1. Exposure to particulate matter less than 2.5 um in diameter was identified as an environmental risk factor for pediatric asthma. 2. Family related risk factors for pediatric asthma include parental asthma, maternal smoking...

1. The SHISA3 gene was found to be silenced through promoter methylation at higher levels in breast cancer tissues compared to normal breast tissues. Evidence Rating Level: 1 (Excellent) Breast cancer (BC) accounts for 15% of tumor related deaths in women, translating to over 627,000 deaths worldwide in 2018 alone. Late...

Prior tonsillectomy is associated with an increased risk of esophageal adenocarcinoma 1. Having a prior tonsillectomy was correlated to a greater risk of developing esophageal adenocarcinoma, with an odds ratio of 1.7. Evidence Rating Level: 2 (Good) Esophageal adenocarcinoma (EAC) is a subtype of esophageal cancer that has gradually grown in incidence...

1. In this observational study involving women aged 70 to 84 years with a life expectancy of at least 10 years, continuing screening past the age of 75 offered no survival benefits versus stopping screening. 2. Participants in the “stop screening” group were, on average, more likely to be diagnosed...

1. Certain dietary supplements, including vitamin B12, iron and omega-3 fatty acids, may negatively impact disease-free survival and overall survival in breast cancer patients undergoing chemotherapy Evidence Rating Level: 2 (Good) While the use of dietary supplements during cancer treatment is not uncommon, there is little data available to support current...

Association of prehospital plasma transfusion with survival in trauma patients with hemorrhagic shock when transport times are longer than 20 minutes: A post-hoc analysis of the PAMPer and COMBAT clinical trials 1. Prehospital plasma transfusion is associated with increased survival in the setting of hemorrhagic shock, particularly with longer transport...