Pyrotinib in combination with trastuzumab and docetaxel promising for HER2 positive metastatic breast cancer
1. This phase 3 randomised trial demonstrated that compared with placebo in combination with trastuzumab and docetaxal, pyrotinib in the ...
Tag: Breast Cancer
Sacituzumab govitecan shows survival benefit in endocrine-resistant hormone-positive metastatic breast cancer
1. Median overall survival increased by 3.2 months in the sacituzumab govitecan group compared to chemotherapy. 2. One fatal treatment-related ...
Multicancer early detection blood tests show promise but warrant further clinical evaluation
1. One-third of patients with a cancer signal were correctly diagnosed to have cancer. 2. Patients in the true-positive group ...
Psychological resilience and spiritual well-being may be associated with supportive care needs in breast cancer patients
1. In this cross-sectional study, there was a significant negative relationship between supportive care needs and spiritual well-being and between ...
Wellness Check: Spirituality
Spiritual care is associated with improved quality of life in patients who underwent intracranial hemorrhage surgery 1. This randomized controlled ...
Breast-conserving surgery is an appropriate procedure for centrally located breast cancer
1. Patients with centrally located breast cancer (CLBC) had higher breast cancer-specific survival (BCSS) and overall survival (OS) rates. 2. ...
Omission of axilla surgery is non-inferior to sentinel lymph node biopsy in female patients with small breast cancers and clinically negative axillary lymph nodes
1. 5-year distant disease-free survival was comparable between both groups. 2. 5-year overall survival was similar between groups. Evidence Rating ...
Breast cancer screening discrepancies in different countries associated with different outcomes
1. In Brasil, Russia, India, China, and South Africa, the availability of breast cancer screening programs was associated with a ...
Endocrine therapy and breast-conserving surgical management without follow-up radiotherapy is safe in low-risk, luminal A subtype breast cancer
1. 5-year recurrence incidence was 2.5% at follow-up. 2. Overall survival at 5 years without radiotherapy was 97.2%, with a ...
Pyrotinib plus capecitabine for trastuzumab-resistant, HER2-positive advanced breast cancer (PICTURE)
1. This phase 2, single-arm, multicenter trial found that in HER2-positive breast cancer patients demonstrating resistance to trastuzumab, the combination ...
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