Tag: cardiac events

1. Combined use of intracoronary near-infrared spectroscopy (NIRS) and intravascular ultrasound were effective at detecting untreated intracoronary lesions at high risk of major adverse cardiac event (MACE). 2. Highly lipidic lesions and large plaque burden were found to be independent predictors of non-culprit lesion-related MACEs. Evidence Rating Level: 2 (Good) Study Rundown:...
1. The PRAISE score showed accurate discriminative capabilities for the prediction of all-cause death, acute myocardial infarction, and major bleeding after an acute coronary syndrome. 2. Compared with low risk stratification, a high-risk PRAISE score was associated with a 58.8-times increase in death, 27.7-times increase in myocardial infarction, and a...
1. There does not appear to be any difference in outcome between pre- and post-treatment administration of P2Y12 inhibitors among patients experiencing a non-ST elevation acute coronary syndrome with planned invasive intervention. 2. Prasugrel and ticagrelor showed similar outcomes when administered post-treatment. Evidence Rating Level: 1 (Excellent) Though it is well established...
1. Of pediatrics patients with left axis deviation (LAD) found incidentally on electrocardiogram (ECG), only 15% of patients had heart disease (HD) on further work up. 2. Features indicating the possibility underlying HD included those patients with a more severe degree of LAD, those with chamber enlargement or hypertrophy, and...
1. Based on data from the Multi-Ethnic Study of Atherosclerosis (MESA) cohort, resting heart rate (HR) lower than 50 beats per minute was only associated with worse outcomes if patients were taking HR-lowering medications. In contrast, HR greater than 80 beats per minute (bpm), regardless of HR-lowering medications, was...
1. From this cross-sectional study, survivors of pediatric cancer who received cardiotoxic therapy experienced high rates of cardiomyopathy, coronary artery disease, valvular disease, and electrical and rhythm abnormalities. 2. The vast majority of those with cardiovascular disease were asymptomatic. Evidence Rating Level: 2 (Good) Study Rundown: Children with many types of once-dire...
1. From a retrospective cohort study, early repolarization (also known as J-wave, QRS slur or QRS notch) was not linked to increased risk of cardiovascular death at 10 years follow-up. Evidence Rating Level: 2 (Good) Study Rundown: Early repolarization (ER), defined as the J-wave pattern (also known as QRS slur or QRS...
Image: PD 1. At 8 years median follow-up, trastuzumab treatment for HER2-positive breast cancer is associated with slightly increased rates of CHF (Congestive heart failure) and LVEF (Left ventricular ejection fraction) decrease but not cardiac death. 2. The associated increases occurred mostly during the treatment interval and were almost all reversible. Evidence...