Tag: degarelix

1. Men with pedophilic disorder treated with gonadotropin-releasing hormone antagonist degarelix were at significantly lower risk of committing sexual abuse 2 weeks following initial injection, as measured by a composite risk score. Evidence Rating: 1 (Excellent) It is estimated that roughly half of child sexual offenders have pedophilic disorder, defined as...

Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial 1. Adults with severe COVID-19 treated with remdesivir had numerically faster time to clinical improvement compared to controls, but the difference was not statistically significant Evidence Rating: 1 (Excellent) Months into declaration of COVID-19 as a pandemic, there still remains...

Ovarian function suppression (OFS) is considered an important aspect of treatment in premenopausal women with advanced endocrine-responsive breast cancer. Degarelix is a gonadotropin-releasing hormone (GnRH) antagonist, which, when bound to GnRH receptors in the pituitary, results in a decreased secretion of gonadotropins. In men, this leads to a rapid...

Ovarian function suppression (OFS) is considered an important aspect of treatment in premenopausal women with advanced endocrine-responsive breast cancer. Degarelix is a gonadotropin-releasing hormone (GnRH) antagonist, which, when bound to GnRH receptors in the pituitary, results in a decreased secretion of gonadotropins. In men, this leads to a rapid...

Association between antithrombotic medication use after bioprosthetic aortic valve replacement and outcomes in the Veterans Health Administration system Patients that have undergone bioprosthetic aortic valve replacement (bAVR) are at an increased risk of thromboembolism. Recommendations and strategies surrounding the use of antithrombotic medications, however, vary. In this retrospective cohort study,...