Tag: fetal hemoglobin

CRISPR-mediated gene activation rescues obesity caused by haploinsufficiency [PreClinical]

CRISPR-Cas9 promoting fetal hemoglobin production improves severe sickle cell disease

byNhat Hung (Benjamin) Lamand1 others

September 13, 2023

1. In this randomized controlled trial, infusion of OTQ923 disrupted inhibitory HBG1 and HBG2 promoter regions of the gamma-globin gene. ...

The REACH trial: hydroxyurea safe and effective for sickle cell anemia in African children

Hydroxyurea with dose escalation performs better than fixed-dose hydroxyurea in pediatric sickle cell disease

byThomas Suand1 others

June 25, 2020

1. Children with sickle cell disease who received the maximum tolerated dose of hydroxyurea had higher concentrations of hemoglobin and ...

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

No Result

View All Result