Low-dose AAVS3 gene therapy is efficacious for treating patients with hemophilia B
1. Hemophilia B patients treated with the adeno-associated virus (AAV) gene therapy produced dose-dependent sustained factor IX levels. 2. All ...
Tag: hepatology
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Fazirsiran reduces Z-AAT protein production in alpha1-antitrypsin deficiency
1. Fazirsiran is associated with a signifcant reduction of Z-AAT protein concentration in the serum and liver of those with ...
Evaluation of early vs standard liver transplant for alcohol-associated liver disease
1. In a cohort of patients with alcoholic liver disease, adherence to a 6-month abstinence period prior to liver transplant ...
Efruxifermin an effective and safe treatment for nonalcoholic steatohepatitis
1. Efruxifermin was an effective and safe treatment found to significantly reduce hepatic fat fraction in order to treat nonalcoholic ...
Liver fibrosis in post-PCI patients associated with higher incidence of cardiovascular events
1. Post-PCI patients with intermediate to high liver fibrosis scores were observed to experience higher incidences of major cardiovascular events. ...
Adjunctive methylprednisolone treatment for hepatitis B acute-on-chronic liver failure associated with increased survival rate
1. Adding methylprednisolone to standard treatment in hepatitis B virus-related acute-on-chronic liver failure was associated with an increase in 6-month ...
2 Minute Medicine Rewind December 9, 2020
Risk of mortality associated with concomitant antidepressant and benzodiazepine therapy among patients with depression: a population-based cohort study 1. Concomitant ...
No benefit of erlotinib in combined hepatocellular carcinoma treatment
1. In a phase III trial of over 700 patients with hepatocellular carcinoma (HCC), there was no significant difference in ...