Tag: hpv

1. Among a cohort of college-age young adults, having appropriate knowledge of the HPV vaccine was associated with increased uptake, while high uncertainty was associated with decreased uptake. Evidence Rating Level: 2 (Good) Study Rundown: Human papillomavirus (HPV) is the most common sexually transmitted infection in the U.S., and can lead...
1. Among a cohort of college-age young adults, having appropriate knowledge of the HPV vaccine was associated with increased uptake, while high uncertainty was associated with decreased uptake. Evidence Rating Level: 2 (Good) Study Rundown: Human papillomavirus (HPV) is the most common sexually transmitted infection in the U.S., and can lead...
1. The FDA approved the expansion of the human papillomavirus (HPV) vaccination from ages 9 to 26 in women and 21 in men to 45 years in men and women. 2. This study predicted a small reduction in HPV-associated diseases and a substantially higher incremental cost-effectiveness ratios with extending the...
Surgery for Drug-Resistant Epilepsy in Children The role of surgery in cases of drug-resistant recalcitrant epilepsy in children and adolescents is currently unclear.  In this randomized control trial, 116 patients age 18 years or younger were randomized to receive neurosurgery and medical therapy or medical therapy alone to determine whether...
Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation Patients with atrial fibrillation undergoing percutaneous coronary intervention (PCI) typically receive warfarin and two antiplatelet drugs as part of the current standard of care. However, studies have shown that this approach is associated with an increased risk of major bleeding....
Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery There is currently a lack of consensus on how to best prevent intraoperative hypotension. Whether blood pressure (BP) management should be an individualized strategy, where the target threshold is adjusted to...
1. In this combined post-hoc analysis of two phase 3, double-blind randomized trials, the bivalent HPV-16/18 vaccine AS04 was effective and conferred similar levels of protection to women after 3, 2, or 1 doses. Evidence Rating Level: 1 (Excellent) Study Rundown: Prevention against cervical cancer with 3 doses of...
1. As near-universal human papillomavirus (HPV) vaccination of girls is achieved, the burden of HPV-related cancers in men can be reduced by 66%. 2. Vaccinating boys can largely be beneficial in preventing anal carcinomas, specifically in men who have sex with men. Evidence Rating Level: 2 (Good)            Study Rundown:...
1. From a cross-sectional study of women aged 15-25 years, women who self-identified as lesbians and had heard of the HPV vaccine were less likely to have initiated vaccination than heterosexuals. 2. Women who did not report their sexual orientation, predominantly Latina immigrants of lower socioeconomic status, were significantly less...
1. Patients with CIN-2 who were treated with hexaminolevulinate 5% photodynamic therapy showed histological improvement. 2. This treatment method also demonstrated efficacy at clearance of HPV in patients with CIN-2. Evidence Rating Level: 1 (Excellent)   Study Rundown: Worldwide, cervical cancer is the leading causes of cancer death for women. Existing practices,...