Tag: hydroxychloroquine (Plaquenil)

1. Metformin was found to be safe and tolerable in survivors of pediatric brain tumors. 2. Metformin was associated with retention of memory and processing speed abilities, as well as a reduction of white matter loss. Evidence Rating Level: 1 (Excellent) It is believed that endogenous neural precursor cells (NPCs) can promote...
1. In this double-blind, randomized trial, hydroxychloroquine did not reduce symptom severity in an adult, outpatient population. 2. More side effects, mainly gastrointestinal symptoms, were experienced by the patients in the treatment group. Evidence Rating Level: 1 (Excellent) Study Rundown: There are currently no effective oral therapies for the outpatient treatment of...
1. Hydroxychloroquine treatment was found to significantly reduce viral load in COVID-19 patients, and had an enhanced effect when azithromycin was included in treatment Evidence Rating: 4 (Below Average) Despite significant research efforts, there currently exists no approved pharmacolgic therapy for the direct treatment of COVID-19 to reduce viral load. Significant...
1. For radiographic osteoarthritis and hand pain that is moderate to severe, hydroxychloroquine (HCQ) does not show any greater effectiveness than placebo for reducing overall hand pain. 2. There was also no significant difference between HCQ and placebo for secondary end points including function, grip strength, radiographic structural damage, and...
1. After 24 weeks of treatment, hydroxychloroquine was no more effective than placebo in improving scores for dryness, pain, and fatigue in Sjogren’s Syndrome. Evidence Rating Level: 2 (Good) Study Rundown: Sjogren’s Syndrome (SS) is an autoimmune disease that results in dry eyes, dry mouth, joint and muscle pain, and less...