Tag: Levetiracetam

1. Antiepileptic drug exposure in infants of breastfeeding mothers being treated for epilepsy is low. Evidence Rating Level: 2 (Good) While breastfeeding for the first 6 months of life is currently recommended by the American Academy of Pediatrics, no consensus exists for the safety of breastfeeding when the mother is receiving antiepileptic...
Association Between Immune-Related Adverse Events and Recurrence-Free Survival Among Patients With Stage III Melanoma Randomized to Receive Pembrolizumab or Placebo: A Secondary Analysis of a Randomized Clinical Trial 1. Immune-related adverse events are associated with a longer recurrence-free survival in patients with stage III melanoma treated with pembrolizumab. Evidence Rating Level:...
Convulsive status epilepticus (SE) is the most common life-threatening neurological emergency in pediatrics. It is associated with significant morbidity and mortality, with 22% of patients ultimately requiring intubation and intensive care unit admission. Benzodiazepines are used first-line in terminating seizure activity. However, when this fails, phenytoin is the current...
Screening for breech presentation using universal late-pregnancy ultrasonography: A prospective cohort study and cost effectiveness analysis Fetal presentation has long been determined by way of clinical examination only, despite the relative ease with which breech presentation can be identified through ultrasound screening. As such, many women continue to present in...
Image: PD 1. Exposure to levetiracetam in utero was not associated with increased developmental or language delays in children at ages 3-4.5 years. 2. Children exposed to valproic acid in utero scored lower on gross motor, comprehension and language skill assessments at 3-4.5 years compared to those exposed to levetiracetam. Evidence Rating...