Previous studies have suggested that certain hormonal contraceptive methods, including intramuscular depot medroxyprogesterone acetate (DMPA-IM), may increase women’s susceptibility to HIV acquisition. In this randomized, open-label trial, 7829 women living in areas of high HIV incidence in Africa were randomly assigned to receive DMPA-IM (n=2609), a copper intrauterine device...
1. Lower-dose 13.5 mg and 19.5 mg levonorgestrel intrauterine contraceptive systems (IUDs) were found to be highly effective for up to 3 years.
2. Both devices were easy to insert and well tolerated by paras and nulliparas.
Evidence Rating Level: 1 (Excellent)
Study Rundown: This phase III clinical...
Image: PD. Levonorgestrel molecule.
1. Overall, intrauterine devices had a very low rate of serious complications (<1%) in both teenagers and older women.
2. Levonorgestrel-releasing intra-uterine device (IUD) was associated with fewer complications and less early discontinuation than the copper IUD in all age groups.
Evidence Rating Level: 2 (Good)
Study Rundown: The...