Tag: low density lipoprotein (LDL)

1. In this study, improved sleep quality was associated with significantly decreased systolic blood pressure and increased high-density lipoprotein levels after 24 months. 2. Increased time to sleep was also associated with decreased low-density lipoprotein levels, after 24 months. Evidence Rating Level: 1 (Excellent) Sleep has endocrinologic implications, which may impact...
1. In individuals aged 70-100 years, there was a significantly increased risk of myocardial infarction and atherosclerotic cardiovascular disease for every 1.0 mmol/L increase in LDL cholesterol. 2. Individuals aged 80-100 years were found to have the lowest number needed to treat in 5 years to prevent one myocardial infarction. Evidence...
 1. In patients aged ≥75 years, LDL cholesterol-lowering therapies reduced the risk for major vascular events, including cardiovascular death, myocardial infarction, stroke, and coronary revascularization. 2. In older patients (≥75 years), the benefits in risk reduction were similar when compared to younger patients (< 75 years), and when comparing statin...
1. Evolocumab successfully reduced low density lipoprotein (LDL) cholesterol levels in pediatric patients with heterozygous familial hypercholesterolemia. 2. Non- high density lipoprotein and apolipoprotein B levels were also improved in the evolocumab group. Evidence Rating Level: 1 (Excellent) Study Rundown: In the adult patient population with hyperlipidemia, human monoclonal antibodies that inhibitor...