Tag: metastasis
Click to read the study in JAMA Network Open.
Gastric cancer is typically treated with surgical resection followed by chemotherapy. Peritoneal metastasis, caused by direct cancer cell dissemination, is the most common pattern of postoperative recurrence; the prognosis of patients with peritoneal metastasis is very poor. Extensive intraoperative peritoneal lavage (EIPL) is one strategy that has been developed...
1. Dually injecting mice featuring lymph node cancer metastases with a non-targeted fluorescent antibody (noTRGT) and a cancer-targeted fluorescent antibody (TRGT) allowed for determination of cancer-receptor concentrations in the lymph nodes.
2. The calculated concentrations of the cancer-receptor strongly correlated with the number of tumor cells in a given tumor,...
1. Supraclavicular lymph node (SCLN) positive patients with esophageal cancer, who were subsequently SCLN negative after neo-adjuvant chemotherapy, were not shown have a decreased 3-year survival rate following esophagectomy compared to patients who were originally SCLN negative.
Evidence Rating Level: 2 (Good)
Study Rundown: Esophageal cancer is a particularly...
1.Diffusion-weighted magnetic resonance imaging (DWMRI) was shown to be both sensitive and specific for identification of pelvic lymph node metastases among patients with prostate or bladder cancer.
2. The inclusion of several additional imaging criteria in conjunction with DWMRI reduced the number of diagnostic errors and was associated with superior...
Image: PD
1. Adding angiogenesis-targeted sunitinib therapy to prednisone in the treatment of metastatic castration-resistant prostate cancer (mCRPC) does significantly improves progression-free survival, but not overall survival.
2. The potential uses of anti-angiogenic therapy in this setting requires further investigation.
Evidence rating level: 1 (Excellent)
Study Rundown: The standard approach to managing metastatic,...