Tag: moderate-to-severe atopic dermatitis

1. The findings of this longitudinal cohort study suggest an association between atopic dermatitis and symptoms of depression and internalizing behaviors starting in early childhood and persisting through adolescence. 2. With the global prevalence of atopic diseases increasing in children, health care providers must be cognizant of the psychosocial needs...
1. Upadacitinib combined with topical corticosteroids reduced Eczema Area and Severity Index (EASI) and Investigator’s Global Assessment for atopic dermatitis (vIGA-AD) scores significantly more than placebo with corticosteroids. 2. Efficacy of upadacitinib combination therapy was comparable to upadacitinib monotherapy, suggesting potential for steroid-sparing treatment of atopic dermatitis. Evidence Rating Level: 1...
1. The proportion of patients with EASI ≥75% was significantly greater in the upadacitinib 30 mg and 15 mg groups than the placebo group. 2. Both upadacitinib doses were well tolerated, with the most common adverse events being acne and upper respiratory tract infection. Evidence Rating Level: 1 (Excellent) Study Rundown: Upadacitinib...