Tag: mri

Classics Series, Landmark Trials in Medicine
1. Among patients with acute neurologic deficits presenting within six hours of symptoms onset, diffusion-weight magnetic resonance imaging (DWI) was shown to be significantly more sensitive and specific for the diagnosis of ischemic stroke than non-contrast computed tomography (NCCT). Original Date of Publication: September 2002 Study Rundown: Thrombolysis is a widely...
1. The use of an injectable fluorinated carbohydrate during magnetic resonance imaging allowed for identification and quantification of macrophage foam cells in a mouse model of atherosclerosis, providing proof-of-concept for a high-resolution imaging evaluation of atheromatous inflammation. Evidence Rating Level: 2 (Good) Study Rundown: Atherosclerotic plaque is the fundamental...
1. Among women with suspicious breast lesions, 7 tesla (T) magnetic resonance (MR) imaging with diffusion weighting and combined parallel and readout-segmented echo-planar imaging (rs-EPI) showed a high diagnostic accuracy with fewer technical issues than previously-described 7T techniques. 2. Total image acquisition was less than 4 minutes in length, significantly...
1. Contrast-enhanced magnetic resonance (MR) imaging-derived quantitative parameters of tissue permeability, particularly the volume transfer constant (Ktrans), showed moderate sensitivity and high specificity for differentiation of post-treatment glioblastoma progression from pseudoprogression. Evidence Rating: 3 (Average) Study Rundown: An aggressive brain tumor with a poor prognosis, glioblastoma multiforme, is typically treated with...
 1. In this proof-of-concept study, central thoracic magnetic resonance lymphangiography (MRL) was successfully used to characterize the presence or absence of disease within the central lymphatic vessels in a small series of patients. Evidence Rating Level: 4 (Below Average) Study Rundown: Lymphatic pathology, whether congenital or acquired, can lead to lymphedema, chylothorax,...
1. Among cognitively-intact elderly adults, magnetic resonance (MR) imaging using an arterial spin labeling (ASL) technique was shown to predict cognitive decline after 18 months of follow-up. 2. Similar ASL neuroimaging findings were identified in healthy patients that progressed to cognitive decline as compared to control subjects with known mild...
1. Using cardiac magnetic resonance imaging (MRI), an association was found between infarct severity in patients with reperfused ST segment elevation myocardial infarction (STEMI) and poorer functional recovery of the left ventricle (LV). 2. Cardiac biomarker assessment showed that the presence of microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH)...
1. The combination of positron-emission tomography (PET) and magnetic resonance imaging (PET/MR) was shown to be equivalent to the combination of PET and computed tomography (PET/CT) for whole-body cancer staging and restaging. 2. PET/MR may be more sensitive for distant metastases than PET/CT while being more susceptible to imaging artifacts...
1. The combination of an annual MRI and mammography in women at high risk for breast cancer demonstrated a high breast cancer detection rate.  2. The positive predictive value was higher for cancer detection by both MRI and mammography compared to MRI alone.  Evidence Rating Level: 2 (Good)  Study Rundown: Though only a...
1. Patients having received preoperative magnetic resonance imaging (pMRI) experienced longer times to surgery and a higher rate of contralateral prophylactic mastectomy (CPM).  2. Rates of reoperation were not dependent on patients having undergone pMRI testing.  Evidence Rating Level: 3 (Average)  Study Rundown: The use of pMRI testing for breast cancer patients...