Tag: mRNA-1273 vaccine

Section 2: Moderna Vaccine Second to Receive Emergency Use Authorization The FDA Advisory Committee met on December 17, 2020, ultimately recommending the Moderna vaccine’s approval for emergency use in the prevention of COVID-19. After hospitals across the U.S. began to receive batches of the Pfizer/BioNTech vaccine, Moderna has become the...
1. Administration of mRNA-1273 to rhesus macaques induced ACE2 binding inhibition and neutralizing activity that were orders of magnitude higher than was measured in specimens of human convalescent-phase serum. 2. No vaccine-related pathological changes were observed in lung tissue. Evidence Rating Level: 2 (Good) Study Rundown: As the Covid-19 pandemic continues to...
1. Nonhuman primate vaccination with messenger RNA (mRNA)-1273 induced rapid neutralizing activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 2. The mRNA-1273 vaccine conferred upper and lower airway protection with no pathologic changes in the lungs. Evidence Rating Level: 1 (Excellent) Study Rundown: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is...
1. The mRNA-1273 SARS-CoV-2 (COVID-19) vaccine was shown to be safe and immunogenic amongst the 45 COVID-19 negative participants in this phase 1 clinical trial, when compared to serum convalescent plasma 2. Only patients in the highest 2 dosage groups experienced a severe febrile episode after the 2nd dose was...