Tag: multisystem inflammatory syndrome in children (MIS-C)

1. In this single-center study of children hospitalized with MIS-C, most had complete recovery of cardiac function. 2. While most markers of inflammation normalized rapidly, the proportion of double-negative T-cells (DNTs) remained elevated in nearly all patients at the 4 to 9 month follow up. Evidence Rating Level: 2 (Good) Study...
1. In this cohort study, multisystem inflammatory syndrome in children was a rare but serious complication associated with SARS-CoV-2 infection. 2. The findings of increased incidence among younger people and those from ethnic minority groups emphasizes a need for further identification and risk stratification for multisystem inflammatory syndrome in children. Evidence...
1. In a large French national surveillance study of hospitalized children with COVID-19, age ≥ 10 years, hypoxemia, and extremely elevated C-reactive protein (CRP) were associated with severe disease. 2. In contrast to previous studies, children < 90 days old were at lowest risk of severe disease. Evidence Rating Level: 2...
1. Presentation with shock in the setting of multisystem inflammatory syndrome in children (MIS-C) was associated with worse outcomes 2. Shorter duration of MIS-C symptoms prior to hospital admission was associated with poor outcomes Evidence Rating Level: 2 (Good) Study Rundown: MIS-C is a complication of SARS-CoV-2 that has led to severe...
1. Children with MIS-C had higher titers of SARS- CoV-2 antibodies compared to patients with Kawasaki disease, COVID-19, and hospitalized controls. 2. Levels of SARS-CoV-2 antibodies correlated with higher erythrocyte sedimentation rate (ESR) and length of hospital and ICU stay Evidence Rating Level: 2 (Good) Study Rundown: Although the majority of children...