Tag: neonatology

1. Very low birth weight (VLBW) infants who received antibiotics for 4 to 7 days had significant increased odds of short term morbidity and mortality. 2. Each day of antibiotic use among VLBW infants was associated with about 5% greater odds of major adverse outcomes. Evidence Rating: 2 (Good) Study Rundown: Early...
1. There were no significant differences in rates of bronchopulmonary dysplasia (BPD) and mortality at 36 weeks’ postmenstrual age (PMA) as a composite outcome in ventilator-dependent very preterm infants who received systemic hydrocortisone versus placebo. However, mortality at 36 weeks’ PMA as an individual outcome, was significantly lower in...
1. Mupirocin was shown to have an overall primary decolonization efficacy of 95% when used to treat Staphylococcus aureus among infants <24 months old admitted to the neonatal intensive care unit (NICU). 2. Almost half of all treated patients who demonstrated primary decolonization and remained in the hospital at day...
1. Systematic review with meta-analysis shows no statistically significant difference in morbidity and mortality outcomes when comparing use of low versus high FiO2 during initial resuscitation of preterm infants (<35 weeks gestational age). 2. Subgroup analyses of data on infants <32 weeks and ≤28 weeks also showed no difference in...
The rate of neurodevelopmental impairment (NDI) in infants born ≤500g in Japan between 2003-2012 was 59%, and the prevalence of NDI did not significantly change over the 10-year period. Evidence Rating Level: 1 (Excellent) Study Rundown: Survival rates for periviable infants have improved over the past decade, but data on rates...
1. In this retrospective cohort study, birth at earlier gestational age (GA) was associated with worse survival rates and increased hospitalization rates in the first 10 years of life, with respiratory diagnoses being the most common reason for admission. 2. Birth at earlier GA was also associated with higher parental-reported...
1. Infants ≥ 34 weeks’ gestational age (GA) comprised 75% of the median proportions of neonatal intensive care unit (NICU) admissions across level II-IV NICUs, and only 15% of this group were considered to be high acuity. Evidence Rating Level: 4 (Below Average) Study Rundown: A recent increase in NICU...
1. Children with a history of neonatal abstinence syndrome (NAS) had higher odds of qualifying for and receiving therapies and services for educational disabilities compared to similar peers without a history of NAS. 2. Classroom therapies or services for developmental delay and speech or language impairment were significantly more common...
1. Within a cohort of infants born extremely preterm (EPT), there were elevated rates of high systolic blood pressure (SBP≥90%ile) and hypertension (SBP≥95%ile) when these children reached school age. 2. School age children with high SBP who were born EPT, were significantly more likely to have been born to mothers...
1. In multivariate analyses, adverse late cranial ultrasound findings (CUS) were an independent risk factor for full scale IQ scores <70 (FSIQ <70). Adverse late cranial ultrasound findings and adverse findings on MRI were independent risk factors for moderate-to-severe disability (MTSD) 2. The positive predictive value (PPV) for adverse cranial ultrasound...