Tag: opioid abuse

1. Co-prescription of benzodiazepines and z-drugs with opioid agonists was associated with a significantly increased risk of drug-related poisoning in opioid-dependent individuals. Evidence Rating Level: 2 (Good) Opioid agonist treatment (OAT) is common and effective for individuals with opioid dependence. Concurrent medications, particularly sedatives, prescribed alongside OAT may increase risk of...

Association between heart failure and postoperative mortality among patients undergoing ambulatory noncardiac surgery Patients with heart failure are at an increased risk of experiencing postoperative adverse events and mortality. While ambulatory surgical procedures are perceived as being low risk, morbidity and mortality outcomes in this surgical setting have not been...

It is not uncommon for adolescents to inappropriately access prescription opioids from friends or family members. Recently, concerns surrounding the use of opioids that are not medically indicated, and an increased risk of initiating heroin use, have surfaced. In this prospective cohort study, 3298 high school students from Los...

The opioid epidemic has been associated with rising hepatitis C virus (HCV) infection incidence in North America among those who inject drugs. While opioid agonist therapy may reduce HCV infection risk, the role of dosage of such therapy on this association is unclear. Given an increasing focus on global...