Tag: prostate cancer

Image: PD  1. Androgen deprivation therapy increases the risk of acute kidney injury in patients with non-metastatic prostate cancer.  2. Past use of androgen deprivation therapy did not significantly increase the risk of acute kidney injury.  Evidence Rating Level: 3 (Average)  Study Rundown: Androgen deprivation therapy (ADT) effectively creates a hypogonadal state for...
Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Geographic Variation in Cardiovascular Procedure Use Among Medicare Fee-for-Service vs Medicare Advantage Beneficiaries  In this retrospective analysis of patients in capitated and fee-for-service Medicare plans, investigators found the capitated Medicare...
Image: PD 1. Daily soy protein powder consumption for 2 years following radical prostatectomy did not reduce biochemical recurrence of prostate cancer in men at high risk of PSA failure.  Evidence Rating Level: 1 (Excellent)  Study Rundown: Daily soy supplementation taken as a powder for two years was not shown to reduce...
Image: PD June 24 – June 30, 2013 In this section, we will highlight the some of the high-impact studies, updates, and analyses published in medicine during the past week. Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack In this multicenter open label RCT, patients with a minor ischemic stroke...
Image: PD/NIH 1. In terms of survival, intermittent androgen deprivation did not reach the pre-defined threshold to be considered non-inferior to continuous therapy in metastatic prostate cancer, and may in-fact compromise survival. 2. Intermittent androgen deprivation led to a short-term improvement in quality of life compared to continuous treatment.  Study Rundown: Androgen...
Jan 31st – NEJM - While 15-year outcomes are similar, at years 2 and 5 years radiotherapy is superior to prostatectomy in urinary and erectile functions. Image: CC/Nephron. Gleason 4 prostatic acinar adenocarcinoma. 1. At 2 years and 5 years from diagnosis, radiotherapy is superior to prostatectomy in such functional outcomes as urinary...